EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a potent

adenosine deaminase Adenosine deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme () involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Its primary function ...

inhibitor, which also acts as a

phosphodiesterase inhibitor A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and c ...

that selectively inhibits phosphodiesterase type 2 (PDE2).

References

PDE2 inhibitors Purines Secondary alcohols {{drug-stub