Duct tape occlusion therapy (DTOT) is a method of treating

wart Warts are typically small, rough, hard growths that are similar in color to the rest of the skin. They typically do not result in other symptoms, except when on the bottom of the feet, where they may be painful. While they usually occur on the ...

s by covering them with

duct tape Duct tape (also called duck tape, from the cotton duck cloth it was originally made of) is cloth- or scrim-backed pressure-sensitive tape, often coated with polyethylene. There are a variety of constructions using different backings and adhesi ...

for prolonged periods. The manner in which duct tape appears to work is unclear. The tape might create a

macerating Maceration is the process of preparing foods through the softening or breaking into pieces using a liquid. Raw, dried or preserved fruit or vegetables are soaked in a liquid to soften the food, or absorb the flavor of the liquid into the food. I ...

and

keratolytic Keratolytic () therapy is a type of medical treatment to remove warts, calluses and other lesions in which the epidermis produces excess skin. In this therapy, acidic topical medicines, such as Whitfield's ointment or Jessner's solution, are ap ...

environment, stimulating an

immune response An immune response is a reaction which occurs within an organism for the purpose of defending against foreign invaders. These invaders include a wide variety of different microorganisms including viruses, bacteria, parasites, and fungi which could ...

. The type of adhesive in the duct tape is likely to be important as leeching of the adhesive into the skin may be causing the immune system response.

Side effect In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequence ...

s can include skin irritation and peeling. There is mixed evidence that occlusive treatment with various types of duct tape is effective. Clinical trials in 2012 concluded that no statistically significant difference between clear duct tape and

placebo A placebo ( ) is a substance or treatment which is designed to have no therapeutic value. Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery, and other procedures. In general, placebos can af ...

could be determined within the sample. On health information websites, duct tape is referred to as a treatment with mixed evidence of efficacy, no good evidence or described as alternative medicine. Despite the mixed evidence for efficacy, the simplicity of the method and its limited side-effects leads some researchers to be reluctant to dismiss it. __TOC__

Evidence

In 1978, Jerome Z Litt was the first to suggest that adhesive tape could be used to treat warts on the fingers. He claimed: "My method is safe, easy, simple, painless, inexpensive, and highly effective. It leaves no scarring or deformed nails. The mystery remains: How and why does this method work? I cannot offer any reasonable or logical explanation. It cannot be all 'hypnotic' or 'suggestive.' Could it be that the airtight occlusion and a chemical reaction set up by the adhesive in the tape might combine to release a chemical or '

toxin A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849 ...

' causing the formation of antibodies? Whatever it may be, it works. I recommend that you try it." A 2002 study involved 51 individuals (aged 3–22) treated with either "standard duct tape" (not otherwise specified in the study) or cryotherapy. A piece of duct tape was cut as close to the size of the wart as possible, and applied to the area. The tape was left on for 6 days and replaced with new duct tape if it fell off. After 6 days, the tape was removed, the area soaked in water, and the wart

debride Debridement is the medical removal of dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue. Removal may be surgical, mechanical, chemical, autolytic (self-digestion), and by maggot therapy. In po ...

d with an

emery board A nail file is a tool used to gently grind down and shape the edges of nails. They are often used in manicures and pedicures after the nail has been trimmed using appropriate nail clippers. Nail files may either be emery boards, ceramic, glass, ...

pumice stone Pumice (), called pumicite in its powdered or dust form, is a volcanic rock that consists of highly vesicular rough-textured volcanic glass, which may or may not contain crystals. It is typically light-colored. Scoria is another vesicular vol ...

. The tape was left off overnight and reapplied on the following morning. This process continued for up to 2 months or until the wart was resolved, whichever occurred first. Progress was monitored every 4 weeks. The researchers found the duct tape treatment significantly more effective than the cryotherapy (P=0.05) with 85% in the duct tape treatment group having a complete resolution of their wart, compared to 60% in the cryotherapy group. The study was criticized due to lack of a placebo control group, and because a number of outcome assessments were done by phone. There was also no reported long term follow up to ensure no recurrence of the warts. Two later studies failed to repeat the results of the 2002 study. One compared duct tape with

moleskin Moleskin is a heavy cotton fabric, woven and then shorn to create a short, soft pile on one side. The feel and appearance of its nap is suede-like, less plush than velour and more like felt or chamois. The word is also used for clothing made fr ...

, finding no statistically significant difference in results reported between the two groups. Both studies used 3M clear duct tape, again concluding no statistically significant effect on wart resolution. The statistical power of the latter trial has been questioned, and it has been suggested that duct tape occlusion therapy only works with rubber-based adhesives, whereas these studies utilized acrylic-based adhesive.

References

{{DEFAULTSORT:Duct Tape Occlusion Therapy Dermatologic procedures Alternative medical treatments