Dilazep is a

vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, ...

that acts as an

adenosine reuptake inhibitor An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs). This i ...

. It is used for the treatment of

cardiopathy Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, hea ...

and

renal disorder The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; bloo ...

Synthesis

The reaction of bis-(3-hydroxypropyl)-ethylene diamine (1) with 1-Bromo-3-chloropropane (2) gives homopiperazine 9970-80-0 (3). Esterification by reaction with 3,4,5-Trimethoxybenzoyl Chloride 521-61-3(4) completed the synthesis of Dilazep (5).

References

Vasodilators Pyrogallol ethers Benzoate esters Diazepanes Adenosine reuptake inhibitors {{cardiovascular-drug-stub

Synthesis

See also

References