Dihydrouracil is an intermediate in the catabolism of
uracil
Uracil () (symbol U or Ura) is one of the four nucleobases in the nucleic acid RNA. The others are adenine (A), cytosine (C), and guanine (G). In RNA, uracil binds to adenine via two hydrogen bonds. In DNA, the uracil nucleobase is replaced by ...
.
It is the base present in the
nucleoside
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed a nitrogenous base) and a five-carbon sugar (ribose or 2'-deoxyribose) whereas a nucleotide ...
dihydrouridine
Dihydrouridine (abbreviated as D, DHU, or UH2) is a pyrimidine nucleoside which is the result of adding two hydrogen atoms to a uridine, making it a fully saturated pyrimidine ring with no remaining double bonds. D is found in tRNA and rRNA molec ...
.
See also
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Dihydrouracil dehydrogenase (NAD+)
In enzymology, a dihydrouracil dehydrogenase (NAD+) () is an enzyme that catalyzes the chemical reaction
:5,6-dihydrouracil + NAD+ \rightleftharpoons uracil + NADH + H+
Thus, the two substrates of this enzyme are 5,6-dihydrouracil and NAD+, wh ...
*
Dihydrouracil oxidase
In enzymology, a dihydrouracil oxidase () is an enzyme that catalyzes the chemical reaction
:5,6-dihydrouracil + O2 \rightleftharpoons uracil + H2O2
Thus, the two substrates of this enzyme are 5,6-dihydrouracil and O2, whereas its two products ...
*
Dihydropyrimidinase
In enzymology, a dihydropyrimidinase () is an enzyme that catalyzes the chemical reaction
:5,6-dihydrouracil + H2O \rightleftharpoons 3-ureidopropanoate
Thus, the two substrates of this enzyme are 5,6-dihydrouracil and H2O, whereas its produ ...
References
Nucleobases
Ureas
Pyrimidinediones
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