Desmethoxyfallypride is a moderate affinity
dopamine D2 receptor
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the ''DRD2'' gene. After work from Paul Greengard's lab had suggested that dopamine receptors were the site of action of antipsychotic drugs, several groups, in ...
/D3
receptor antagonist used in medical research, usually in the form of the
radiopharmaceuticals
Radiopharmaceuticals, or medicinal radiocompounds, are a group of pharmaceutical drugs containing radioactive isotopes. Radiopharmaceuticals can be used as diagnostic and therapeutic agents. Radiopharmaceuticals emit radiation themselves, which is ...
desmethoxyfallypride or DMFP(
18F) and has been used in human studies
as a
positron emission tomography (PET)
radiotracer
A radioactive tracer, radiotracer, or radioactive label is a chemical compound in which one or more atoms have been replaced by a radionuclide so by virtue of its radioactive decay it can be used to explore the mechanism of chemical reactions by tr ...
.
References
External links
ChemSpider
{{Dopaminergics
Typical antipsychotics
Salicylamide ethers
Pyrrolidines
D2 antagonists
Organofluorides
Radiopharmaceuticals
Allyl compounds