Dendrocnide moroides

''Dendrocnide moroides'', commonly known in Australia as the stinging tree, stinging bush, Queensland Stinger or gympie-gympie, is a plant in the nettle family Urticaceae found in rainforest areas of Malaysia and Australia. It is notorious for its extremely painful and long-lasting sting. The common name gympie-gympie comes from the language of the Indigenous Gubbi Gubbi people of south-eastern Queensland.

Description

''D. moroides'' is a straggly perennial understory shrub, usually flowering and fruiting when less than tall, but it may reach up to in height. It is superficially similar to '' Dendrocnide cordifolia'', with the most obvious difference being the point of attachment of the petiole to the leaf blade—where ''D. moroides'' is peltate, i.e. the stalk attaches to the underside of the leaf and not at the edge, ''D. cordifolia'' is cordate. The stem, branches, petioles, leaves, and fruits are all covered in stinging hairs.

It has large, heart-shaped, simple leaves about long and wide with toothed margins, a pointed tip and a cordate to obtuse base shape. There are six to eight pairs of lateral veins either side of the midrib. The petiole is quite long, about as long as the leaf blade itself, with stipules around long.

The inflorescence is monoecious (rarely dioecious), and is borne in the leaf axils. It is up to long, often paired. It carries both male and female flowers which are quite small, the perianth measuring less than across. Flowering occurs throughout the year, but mostly in summer.

Fruits of this species are an achene (a tiny seed-like fruit), produced in number in a globular structure which is pink to light-purple in colour and has an appearance similar to a mulberry. Each achene, measuring just long, is contained in a small fleshy sac which derives from the swollen pedicel. As with the rest of this plant, the infructescences are also covered in stinging hairs, but are edible if the hairs are removed.

Taxonomy

The type specimen for this species was collected in 1819 by Allan Cunningham near the Endeavour River, and was first described in 1857 by Hugh Algernon Weddell as ''Laportea moroides'' in his work ''Monographie de la Famille des Urticées'', published in the journal ''Archives du Muséum d'Histoire Naturelle''. The current binomial combination was published by Wee-Lek Chew in ''The Gardens' Bulletin Singapore'' in 1966.

Etymology

The genus name ''Dendrocnide'' has been constructed on the Ancient Greek ''δένδρον'' (déndron), meaning "tree", and ''κνίδος'' (knídos), meaning "stinging needle". The species epithet ''moroides'' is created from the genus name for mulberries ''Morus'', combined with the Latin suffix ''-oides'', meaning "resembling", referring to the mulberry-like infructescence. The binomial name may be translated as "mulberry-like stinging tree".

Distribution and habitat

The species occurs in and near rainforest, from Cape York Peninsula south to northern New South Wales in Australia and also occurs in the Moluccas and Indonesia. It is an early coloniser in rainforest gaps, such as alongside water courses and roads, around tree falls, and in man-made clearings. The seeds germinate in full sunlight after soil disturbance. Although common in Queensland, it is rare in the southernmost part of its range and is listed as an endangered species in New South Wales.

Ecology

''Dendrocnide moroides'' serves as the host plant for larvae of the white nymph butterfly. A variety of insects feed on the leaves, among them the nocturnal beetle '' Prasyptera mastersi'' and the moth '' Prorodes mimica'', as well as the herbivorous Red-legged pademelon, which is unique among mammals in being apparently immune to the plant's neurotoxins. Fruits are eaten by various birds that distribute the seeds in their droppings.

Toxicity

''D. moroides'' is notorious for its extremely painful sting which may leave victims suffering for weeks or even months. Researchers at the University of Queensland recently discovered that the plant produces a neurotoxin similar to that of a spider or cone snail. It is reputed to be the most poisonous plant in Australia, if not the world. After contact with the plant the victim will feel an immediate severe burning and stinging at the site of contact, which then intensifies further over the next 20 to 30 minutes and will last from hours to several days before subsiding. During this time the victim may get little sleep because of the intensity of the pain. In severe cases it may cause urticaria, and the lymph glands under the arms may swell and become painful, and there have been rare cases of hospitalisation.

Mechanism

Very fine, brittle hairs (called trichomes) loaded with toxins cover the entire plant; even the slightest touch will embed them in the skin. Electron micrograph images show that they are similar to a hypodermic needle in being very sharp-pointed and hollow. Additionally, it has been shown that there is a structurally weak point near the tip of the hair, which acts as a pre-set fracture line. When it enters the skin the hair fractures at this point, allowing the contents of the trichome to be injected into the victim's tissues.

The trichomes stay in the skin for up to a year, and release the toxin cocktail into the body during triggering events such as touching the affected area, contact with water, or temperature changes. Ernie Rider, a conservation officer with the Queensland Parks and Wildlife Service, was slapped in the face and torso with the foliage in 1963, and said:

For two or three days the pain was almost unbearable; I couldn't work or sleep... I remember it feeling like there were giant hands trying to squash my chest... then it was pretty bad pain for another fortnight or so. The stinging persisted for two years and recurred every time I had a cold shower...There's nothing to rival it; it's ten times worse than anything else.

Physical contact with ''Dendrocnide moroides'' is not the only way that it can cause harm to a person—the trichomes are constantly being shed from the plant and may be suspended in the air within its vicinity. They can then be inhaled, which may lead to respiratory complications if a person spends time in close proximity to the plant. The Australian entomologist and ecologist Marina Hurley wrote her doctorate studying two ''Dendrocnide'' species of the Atherton Tablelands, west of Cairns, namely ''Dendrocnide moroides'' and '' Dendrocnide cordifolia'', and was exposed to the airborne hairs over a long period of time. She suffered sneezing fits, watery eyes and nose, and eventually developed an allergy that required medical attention. W.V. MacFarlane, who was a Professorial Fellow in Physiology at the John Curtin School of Medical Research at the Australian National University, observed the effects of inhaling the trichomes, and he reported:

The plucking of hairs from the leaves invariably produces sneezing in the operator within 10 or 15 minutes. During early attempts to separate stinging hairs from dried leaves, dust and presumably some hairs were inhaled. Initially they produced sneezing, but within three hours there was diffuse nasopharyngeal pain, and after 26 hours a sensation of an acute sore throat like tonsillitis was experienced.

Pharmacology

The cause of the intense pain has been the subject of scientific research since European explorers first encountered the plant in the mid-19th century. While it is known that a cocktail of toxins is contained within the trichomes, its exact nature was not fully understood . It is known that the active constituents are very stable, since dead leaves found on the forest floor and even decades-old laboratory specimens can still inflict the sting.

Early studies suggested that a variety of compounds, such as histamine, acetylcholine, 5-hydroxytryptamine and formic acid, could be responsible; however none of these has been proven to produce a similar intensity or duration of pain to those exhibited by the sting from the plant. Around 1970 a new compound was identified and given the name moroidin. It was for a time thought possibly to be the causative agent; however later research showed that it did not cause the same effects as a sting from the plant.

In 2020 a previously unknown family of disulfide-rich peptides was identified by a group of researchers and given the name gympietides. These compounds were shown to produce significant pain responses in laboratory tests. Moreover, their complex structure resembling the inhibitor cystine knot made them highly stable, explaining how the sting lasts for such a long time.

There has been anecdotal evidence of some plants having no sting but still possessing the hairs, suggesting a chemical change to the toxin.

Remedies

A commonly recommended first-aid treatment is to use depilatory wax or sticky tape to remove the hairs. The Kuku Yalanji people of Mossman Gorge used a method that was essentially similar, making a juice from the fruits or roots of the plant and applying it to the affected area, before scraping it off with a mussel shell once it had become sticky. Mechanical removal is not always successful however, as the hairs are so tiny that the skin will often close over them, making removal impossible.

Various other treatments, mostly ineffectual, have been tried over time. They include bathing the affected area in hot water, applying papaya ointment, xylocaine or lignocaine cream, and even swabbing with dilute hydrochloric acid. All of these have, at best, temporary effect.

Anecdotal stories

Anecdotes of encounters with Gympie-gympie are numerous, and many can be dismissed as yarns, such as one which involves using the leaves as toilet paper (the user would have been stung when they first picked up the leaf, and unlikely to have proceeded to use it in the intended manner). Nevertheless, some have been documented, such as horses having to be rested after being stung, or even becoming violent and having to be shot. Only one report of a human fatality attributed to any ''Dendrocnide'' species (in this case ''D. cordata'') is confirmed, which occurred in New Guinea in 1922.

Gallery

File:Dendrocnide moroides shrub SF20326.jpg, Mature shrub around 3 metres tall
File:Dendrocnide moroides (Gympie Gympie) 4.jpg , Inflorescence
File:Stinging tree.JPG , Foliage
File:Dendrocnide moroides (Gympie Gympie) 5.jpg , Detail showing stinging hairs
File:Dendrocnide moroides fruits SF21168.jpg, Fruits and leaves

References

External links

Map of observations
of ''Dendrocnide moroides'' at the Australasian Virtual Herbarium.

Queensland’s Gympie-Gympie: the world’s most painful plant
John Oxley Library Blog, State Library of Queensland.

{{Taxonbar, from=Q782859

Bushfood
Dendrocnide
Flora of New South Wales
Flora of Queensland
Flora of the Maluku Islands
Flora of the Lesser Sunda Islands
Rosales of Australia
Poisonous plants