Debi Prasad Sarkar
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Debi Prasad Sarkar (born 15 January 1958) is an Indian
biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and cell parts. The word "biochemist" is a portmanteau of "biological ch ...
, immunologist and virologist. He was the head of biochemistry department and dean FIAS, at the University of Delhi South Campus and served as the director of IISER Mohali from 2017 to 2019. He then resumed his professorship and subsequently promoted to the post of senior professor of biochemistry, with effect from 18 July 2018 at the parent institute, University of Delhi. Serving as joint director, DSSEED, IoE, University of Delhi. On the scientific front, he is renowned for his researches on
Sendai virus ''Murine respirovirus'', formerly ''Sendai virus'' (SeV) and previously also known as murine parainfluenza virus type 1 or hemagglutinating virus of Japan (HVJ), is an enveloped,150-200 nm in diameter, a negative sense, single-stranded RN ...
and developing reconstituted
viral envelope A viral envelope is the outermost layer of many types of viruses. It protects the genetic material in their life cycle when traveling between host cells. Not all viruses have envelopes. Numerous human pathogenic viruses in circulation are encase ...
s. He is an elected fellow of
Indian Academy of Sciences The Indian Academy of Sciences, Bangalore was founded by Indian Physicist and Nobel Laureate C. V. Raman, and was registered as a society on 24 April 1934. Inaugurated on 31 July 1934, it began with 65 founding fellows. The first general meet ...
, National Academy of Sciences, India and
Indian National Science Academy The Indian National Science Academy (INSA) is a national academy in New Delhi for Indian scientists in all branches of science and technology. In August 2019, Dr. Chandrima Shaha was appointed as the president of Indian National Science Acade ...
. The
Council of Scientific and Industrial Research The Council of Scientific and Industrial Research (IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada''), abbreviated as CSIR, was established by the Government of India in September 1942 as an autonomous body that has emerged as the l ...
, the apex agency of the Government of India for scientific research, awarded him the
Shanti Swarup Bhatnagar Prize for Science and Technology The Shanti Swarup Bhatnagar Prize for Science and Technology (SSB) is a science award in India given annually by the Council of Scientific and Industrial Research (CSIR) for notable and outstanding research, applied or fundamental, in biology, ...
, one of the highest Indian Science Awards, in 1998, for his contributions to Biological Sciences. Received Excellence Teacher Award on service by the University of Delhi (99th Foundation Day Celebration of the University of Delhi on 11th September, 2021).


Biography

Debi Prasad Sarkar, born on 15 January 1958, graduated (Honors) in Chemistry in 1978 and obtained a master's degree in biochemistry in 1980 (secured highest marks and awarded BHU Gold Medal), both from
Banaras Hindu University Banaras Hindu University (BHU) IAST: kāśī hindū viśvavidyālaya IPA: /kaːʃiː hɪnd̪uː ʋɪʃwəʋid̪jaːləj/), is a collegiate, central, and research university located in Varanasi, Uttar Pradesh, India, and founded in 1916 ...
. His career started as a senior research fellow at the Biochemistry Department of University of Delhi South Campus in 1985, working on ''Liposomes as immunomodulators and drug delivery using Liposomes'' and he secured a PhD degree for his thesis, ''Immunogenicity of carbohydrate determinants mediated through Liposomes: Liposome-mediated drug delivery'' from the
Calcutta University The University of Calcutta (informally known as Calcutta University; CU) is a Public university, public collegiate university, collegiate State university (India), state university in India, located in Kolkata, West Bengal, India. Considered ...
in 1986. His post-doctoral studies were at the
National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. T ...
of the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the lat ...
where he spent two years (1986–88) as visiting fellow and returned to Delhi University to take up the position of a lecturer of Biochemistry (1988). He stayed at the university for the rest of his academic career, holding various positions as the senior lecturer (1993–96) and reader (1996–2002), to superannuate as a senior professor in 2023.


Legacy

Sarkar's researches on
Sendai virus ''Murine respirovirus'', formerly ''Sendai virus'' (SeV) and previously also known as murine parainfluenza virus type 1 or hemagglutinating virus of Japan (HVJ), is an enveloped,150-200 nm in diameter, a negative sense, single-stranded RN ...
is known to have resulted in the development of reconstituted
viral envelope A viral envelope is the outermost layer of many types of viruses. It protects the genetic material in their life cycle when traveling between host cells. Not all viruses have envelopes. Numerous human pathogenic viruses in circulation are encase ...
s containing only the
fusion protein Fusion proteins or chimeric (kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or more genes that originally coded for separate proteins. Translation of this '' fusion gene'' ...
and this is reported to have assisted in a more efficient gene delivery in therapeutic use. Along with
Vijay Kumar Vijay Kumar may refer to: * Vijay Kumar (cricketer) (born 1975), Indian cricketer * V. S. Vijay Kumar (1944–2019), Indian cricketer * Vijay Kumar (sport shooter) (born 1985), sport shooter and Olympic silver medalist from India * Vijay Kumar ( ...
, he demonstrated for the first time that
HBx HBx is a hepatitis B viral protein. It is 154 amino acids long and interferes with transcription, signal transduction, cell cycle progress, protein degradation, apoptosis and chromosomal stability in the host. It forms a heterodimeric complex w ...
protein stimulated Mitogen-activated signaling cascades in living animals. He continued his researches while working as an academic and holds patents for his inventions. Some of the inventions have resulted in Patent Cooperation Treaties (PCT) earning royalties for the university. He has also participated in clinical trials on behalf of the university, including a preclinical study with a Gunn rat model, in collaboration with
National Research Development Corporation The National Research Development Corporation (NRDC) was a non-departmental government body established by the British Government to transfer technology from the public sector to the private sector. History The NRDC was established by Attlee's Lab ...
and
AECOM AECOM (, ; formerly AECOM Technology Corporation) is an American multinational infrastructure consulting firm. AECOM has approximately 51,000 employees, and is number 157 on the 2019 Fortune 500 list. The company's official name from 1990 t ...
. He has published his research findings in a number of articles and has delivered featured lectures on his work. He has also delivered several award orations including the Prof. B.K. Bachhawat Memorial Lecture of the National Academy of Sciences, India in 2011 and the Platinum Jubilee Lecture at the 102nd edition of the
Indian Science Congress Indian Science Congress Association(ISCA) is a premier scientific organisation of India with headquarters at Kolkata, West Bengal. The association started in the year 1914 in Kolkata and it meets annually in the first week of January. It has a ...
in 2015.


Awards and honors

The
Council of Scientific and Industrial Research The Council of Scientific and Industrial Research (IAST: ''vaigyanik tathā audyogik anusandhāna pariṣada''), abbreviated as CSIR, was established by the Government of India in September 1942 as an autonomous body that has emerged as the l ...
awarded him the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards, in 1998. He received the M. Sreenivasaya Memorial Award of the Society of Biological Chemists (India) in 2005 and the J. C. Bose National Fellowship in 2010. The National Academy of Sciences, India elected him as their fellow in 1996 and the
Indian Academy of Sciences The Indian Academy of Sciences, Bangalore was founded by Indian Physicist and Nobel Laureate C. V. Raman, and was registered as a society on 24 April 1934. Inaugurated on 31 July 1934, it began with 65 founding fellows. The first general meet ...
and the
Indian National Science Academy The Indian National Science Academy (INSA) is a national academy in New Delhi for Indian scientists in all branches of science and technology. In August 2019, Dr. Chandrima Shaha was appointed as the president of Indian National Science Acade ...
followed suit in 2007 and 2011 respectively. Received "Excellence Award for Teachers in service in University of Delhi" on 11th September, 2021 in a function to celebrate 99th Foundation Day of University of Delhi from the Chief Guests Shri Amit Khare, Secretary, MoE, GOI and Shri Imtiaz Ali, renowned film director and producer.


Selected bibliography

* * * * * * * *


See also

*
Viral envelope A viral envelope is the outermost layer of many types of viruses. It protects the genetic material in their life cycle when traveling between host cells. Not all viruses have envelopes. Numerous human pathogenic viruses in circulation are encase ...


Notes


References


External links

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Further reading

* {{DEFAULTSORT:Sarkar, Debi Prasad Recipients of the Shanti Swarup Bhatnagar Award in Biological Science 1958 births Living people Indian immunologists Indian biochemists Indian medical writers Indian virologists Fellows of the Indian National Science Academy Fellows of The National Academy of Sciences, India Banaras Hindu University alumni University of Calcutta alumni National Institutes of Health people 20th-century Indian inventors 20th-century Indian biologists