David Feingold
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David Sidney Feingold (
Hebrew Hebrew (; ; ) is a Northwest Semitic language of the Afroasiatic language family. Historically, it is one of the spoken languages of the Israelites and their longest-surviving descendants, the Jews and Samaritans. It was largely preserved ...
דוד סידני פיינגולד; November 15, 1922 – September 26, 2019) was an American biochemist.


Biography

Feingold was born in
Chelsea Chelsea or Chelsey may refer to: Places Australia * Chelsea, Victoria Canada * Chelsea, Nova Scotia * Chelsea, Quebec United Kingdom * Chelsea, London, an area of London, bounded to the south by the River Thames ** Chelsea (UK Parliament consti ...
,
Massachusetts Massachusetts (Massachusett: ''Muhsachuweesut Massachusett_writing_systems.html" ;"title="nowiki/> məhswatʃəwiːsət.html" ;"title="Massachusett writing systems">məhswatʃəwiːsət">Massachusett writing systems">məhswatʃəwiːsət'' En ...
,
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territori ...
in 1922. In 1944 he graduated from
Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the ...
with a bachelor's degree in chemistry. Following his graduation, he enlisted in the
United States Navy The United States Navy (USN) is the maritime service branch of the United States Armed Forces and one of the eight uniformed services of the United States. It is the largest and most powerful navy in the world, with the estimated tonnage ...
. Feingold served on an
Landing Ship, Tank Landing Ship, Tank (LST), or tank landing ship, is the naval designation for ships first developed during World War II (1939–1945) to support amphibious operations by carrying tanks, vehicles, cargo, and landing troops directly onto shore with ...
in the Pacific for nine months, from 1945 to 1946. From 1947 to 1949 he continued his studies in chemistry at the Chemical Institute at the
University of Zurich The University of Zürich (UZH, german: Universität Zürich) is a public research university located in the city of Zürich, Switzerland. It is the largest university in Switzerland, with its 28,000 enrolled students. It was founded in 1833 f ...
, in Switzerland. In 1949 he moved to Israel. Until 1950, he served in the scientific division of the Israeli Army as a second lieutenant. From 1950 to 1951, he worked at the
Hadassah Hospital Hadassah Medical Center ( he, הָמֶרְכָּז הָרְפוּאִי הֲדַסָּה) is an Israeli medical organization established in 1934 that operates two university hospitals in Jerusalem – one in Ein Karem and one in Mount Scopus –, ...
in
Jerusalem Jerusalem (; he, יְרוּשָׁלַיִם ; ar, القُدس ) (combining the Biblical and common usage Arabic names); grc, Ἱερουσαλήμ/Ἰεροσόλυμα, Hierousalḗm/Hierosóluma; hy, Երուսաղեմ, Erusałēm. i ...
. Between 1951 and 1956, Feingold was a student of biochemistry in
Jerusalem Jerusalem (; he, יְרוּשָׁלַיִם ; ar, القُدس ) (combining the Biblical and common usage Arabic names); grc, Ἱερουσαλήμ/Ἰεροσόλυμα, Hierousalḗm/Hierosóluma; hy, Երուսաղեմ, Erusałēm. i ...
. In 1956 he was awarded a Ph.D. from the Hebrew University of Jerusalem. Following receipt of his PhD he returned to the United States and served as a research assistant at the
University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Franci ...
from 1956 to 1960. In 1960 he moved to the
University of Pittsburgh The University of Pittsburgh (Pitt) is a public state-related research university in Pittsburgh, Pennsylvania. The university is composed of 17 undergraduate and graduate schools and colleges at its urban Pittsburgh campus, home to the univers ...
as an assistant professor in the department of biology. In 1966 he was appointed professor of microbiology at the
University of Pittsburgh School of Medicine The University of Pittsburgh School of Medicine is a medical school of the University of Pittsburgh, located in Pittsburgh, Pennsylvania. The School of Medicine, also known as Pitt Med, is consistently ranked as a "Top Medical School" by '' ...
. He also served as an invited professor in Switzerland,
Brazil Brazil ( pt, Brasil; ), officially the Federative Republic of Brazil (Portuguese: ), is the largest country in both South America and Latin America. At and with over 217 million people, Brazil is the world's fifth-largest country by area ...
, and
Argentina Argentina (), officially the Argentine Republic ( es, link=no, República Argentina), is a country in the southern half of South America. Argentina covers an area of , making it the second-largest country in South America after Brazil, th ...
, as well as at the
University of Colorado The University of Colorado (CU) is a system of public universities in Colorado. It consists of four institutions: University of Colorado Boulder, University of Colorado Colorado Springs, University of Colorado Denver, and the University o ...
. He taught until his retirement in 1993. He died in September 2019 at the age of 96.David Sidney Feingold's obituary
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Awards

In 1957 Feingold was awarded the Israel Prize, in
exact science The exact sciences, sometimes called the exact mathematical sciences, are those sciences "which admit of absolute precision in their results"; especially the mathematical sciences. Examples of the exact sciences are mathematics, optics, astron ...
s, jointly with his research partner Shlomo Hestrin and their student
Gad Avigad Gad Avigad (Hebrew גד אביגד; born 1930) is an Israeli biochemist. Biography Avigad was born in 1930 in Jerusalem. At 17, he joined the ranks of the Palmach. He studied at the Hebrew University of Jerusalem, receiving a doctorate in 1958. ...
.


Published works

* Infection-promoting activity of levan and dextran as a function of degree of polymerization. * Synthesis of sucrose and other β--fructofuranosyl adolases by levansucrase. * An enzymic synthesis of a sucrose analog: α--xylopyranosyl-β-fructofuranoside. * The mechanism of polysaccharide production from sucrose. 4. Isolation and probable structures of oligosaccharides formed from sucrose by a levansucrase system. * Enzymatic synthesis and reactions of a sucrose isomer α--galactopyransoyl β--fructofuranoside. * The structure and properties of levan, a polymer of -fructose produced by cultures and cell-free extracts of ''Aerobacter levanicum''. * Uridine diphosphate ''N''-acetylglucosamine and uridine diphosphate glucuronic acid in mung bean seedlings. * Enzymatic synthesis of uridine diphosphate glucuronic acid and uridine diphosphate galacturonic acid with extracts from ''Phaseolus aureus'' seedlings. * Xylosyl transfer by asparagus extracts. * Sugar nucleotides in the interconversion of sugars of higher plants. * The 4-epimerization and decarboxylation of DUP--glucuronic acid by extracts of ''Phaseolus aureus'' seedings. * Decarboxylation of uridine diphosphate--glucuronic acid by an enzyme preparation from hen oviduct. * Uridine diphosphate -xylose: acceptor xylosyltransferase of '' Cryptococcus laurentii.'' * Interferon production in mice by cell wall mutants of ''Salmonella typhimurium''. * -Rhamnulose 1-phosphate aldolase from ''Escherichia coli''. Crystallization and criteria of purity. * Biosynthesis of uridine diphosphate--xylose. IV. Mechanism of action of UDP-glucuronate carboxyl-lyase. * Biosynthesis of uridine diphosphate--xylose. V. UDP--glucuronate and UDP--galacturonate carboxy-lyase of ''Ampullariella digitata''. * Uridine diphosphate--glucose dehydrogenase of beef liver. Subunit structure and sulfhydryl groups.Uridine diphosphate--glucose dehydrogenase of beef liver. Subunit structure and sulfhydryl groups. Uram, M. Bowser, A. M., Feingold, D. S. and Lamy, F. Anales Asoc. Quim. Argentina 60:135-140, 1972.


See also

* List of Israel Prize recipients * Feingold


References

{{DEFAULTSORT:Feingold, David Sidney 1922 births 2019 deaths American biochemists 20th-century American Jews Hebrew University of Jerusalem alumni Israel Prize in exact science recipients who were biochemists Israel Prize in exact science recipients Massachusetts Institute of Technology School of Science alumni Military personnel from Massachusetts Scientists from Brookline, Massachusetts University of California faculty University of Pittsburgh faculty United States Navy personnel of World War II American expatriates in Switzerland American expatriates in Israel 20th-century Israeli military personnel 21st-century American Jews