David Axelrod may refer to:
* David Axelrod (musician) (1931–2017), American composer, arranger and producer
* David Axelrod (political consultant), (born 1955) senior advisor to former U.S. President Barack Obama.
* David Ha'ivri, David Jason Axelrod Ha'ivri (born 1967), an Israeli settler, political activist
* David Axelrod (physician) (1935–1994), a medical doctor and New York State Commissioner of Health in the 1980s and 1990s; drafted the Libby Zion Law
{{Hndis, Axelrod, David