Darglitazone (previously known as CP 86325-2) is a member of the class of drugs and an agonist of peroxisome proliferator-activated receptor-γ (PPAR-γ), an orphan member of the nuclear receptor superfamily of transcription factors. It has a variety of insulin-sensitizing effects, such as improving glycemic and lipidemic control, and was researched by Pfizer as a treatment of metabolic disorders such as . Its development was terminated on November 08, 1999.

Synthesis

References

{{PPAR modulators Abandoned drugs Oxazoles Thiazolidinediones