''dachshund'' (dac) is a gene involved in the development of the

arthropod Arthropods (, (gen. ποδός)) are invertebrate animals with an exoskeleton, a segmented body, and paired jointed appendages. Arthropods form the phylum Arthropoda. They are distinguished by their jointed limbs and cuticle made of chiti ...

compound eye A compound eye is a visual organ found in arthropods such as insects and crustaceans. It may consist of thousands of ommatidia, which are tiny independent photoreception units that consist of a cornea, lens, and photoreceptor cells which disti ...

which also plays a role in leg development. It is activated by the Distal-less (Dll) gene. Dachshund homologue ( DACH1) regulates

tumorigenesis Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnor ...

in humans as a part of the Retinal Determination Gene Network (RDGN) complex, with cancer patients showing altered DACH1 expression. Its homologs form the SKI/SNO/DAC family ().

References

Arthropod morphology Drosophila melanogaster genes {{Gene-stub