DMeOB is a drug used in scientific research which acts as a
negative allosteric modulator of the
metabotropic glutamate receptor subtype
mGluR5
Metabotropic glutamate receptor 5 is an excitatory Gq-coupled G protein-coupled receptor predominantly expressed on the postsynaptic sites of neurons. In humans, it is encoded by the ''GRM5'' gene.
Function
The amino acid L- glutamate is the ...
.
References
MGlu5 receptor antagonists
Hydrazones
Glutamate receptor negative allosteric modulators
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