D. Lorne Tyrrell
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David Lorne John Tyrrell (born 1943) is a Canadian physician.


Overview

Born on February 10, 1943, in
Edmonton Edmonton ( ) is the capital city of the Canadian province of Alberta. Edmonton is situated on the North Saskatchewan River and is the centre of the Edmonton Metropolitan Region, which is surrounded by Alberta's central region. The city ancho ...
,
Alberta Alberta ( ) is one of the thirteen provinces and territories of Canada. It is part of Western Canada and is one of the three prairie provinces. Alberta is bordered by British Columbia to the west, Saskatchewan to the east, the Northwest Ter ...
, he grew up on the family farm near Duffield and studied at the
University of Alberta The University of Alberta, also known as U of A or UAlberta, is a public research university located in Edmonton, Alberta, Canada. It was founded in 1908 by Alexander Cameron Rutherford,"A Gentleman of Strathcona – Alexander Cameron Rutherfor ...
. Tyrrell interned at the University of Alberta Hospital and then went on to earn a
PhD PHD or PhD may refer to: * Doctor of Philosophy (PhD), an academic qualification Entertainment * '' PhD: Phantasy Degree'', a Korean comic series * ''Piled Higher and Deeper'', a web comic * Ph.D. (band), a 1980s British group ** Ph.D. (Ph.D. albu ...
in
pharmacology Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemica ...
from
Queen's University Queen's or Queens University may refer to: *Queen's University at Kingston, Ontario, Canada *Queen's University Belfast, Northern Ireland, UK **Queen's University of Belfast (UK Parliament constituency) (1918–1950) **Queen's University of Belfast ...
in 1972. He returned to Alberta in 1975 to train in internal medicine. From 1982 to 1994, he was director of the Infectious Diseases division and later the Department of Medical Microbiology and Immunology at the University of Alberta. In 1994, he became dean of the faculty of medicine at the university. In 2010, he secured a large donation for the university which established the Li Ka Shing Institute of Virology. Tyrrell's research into viral hepatitis lead to the development of the oral antiviral drug lamivudine. This treatment enabled the use of liver transplants for persons infected with Hepatitis B. In collaboration with Norman Miles Kneteman (University of Alberta, Department of Surgery), Tyrrell and his team contributed to the development of a mouse with a humanized liver to be used for testing drugs to treat
Hepatitis C Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, a ...
. He was named to the Alberta Order of Excellence in 2000 and became an officer in the
Order of Canada The Order of Canada (french: Ordre du Canada; abbreviated as OC) is a Canadian state order and the second-highest honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the ...
in 2002. Tyrrell became a fellow of the
Royal Society of Canada The Royal Society of Canada (RSC; french: Société royale du Canada, SRC), also known as the Academies of Arts, Humanities and Sciences of Canada (French: ''Académies des arts, des lettres et des sciences du Canada''), is the senior national, bil ...
in 2004. In 2009, he was named chair of the board of directors for the Gairdner Foundation. Tyrrell was inducted into the
Canadian Medical Hall of Fame __NOTOC__ The Canadian Medical Hall of Fame is a Canadian charitable organization, founded in 1994, that honours Canadians who have contributed to the understanding of disease and improving the health of people. It has an exhibit hall in London, O ...
in 2011. He was a
Killam Prize The Izaak Walton Killam Memorial Prize was established according to the will of Dorothy J. Killam to honour the memory of her husband Izaak Walton Killam. Five Killam Prizes, each having a value of $100,000, are annually awarded by the Canada Cou ...
winner in 2015.


References

{{DEFAULTSORT:Tyrrell, D. Lorne 1935 births Living people Canadian infectious disease physicians Fellows of the Royal Society of Canada Members of the Alberta Order of Excellence Officers of the Order of Canada People from Edmonton Queen's University at Kingston alumni University of Alberta alumni