Cutaneous lymphoid hyperplasia refers to a groups of benign cutaneous disorders characterized by collections of
lymphocytes,
macrophage
Macrophages (abbreviated as M φ, MΦ or MP) ( el, large eaters, from Greek ''μακρός'' (') = large, ''φαγεῖν'' (') = to eat) are a type of white blood cell of the immune system that engulfs and digests pathogens, such as cancer cel ...
s, and
dendritic cell
Dendritic cells (DCs) are antigen-presenting cells (also known as ''accessory cells'') of the mammalian immune system. Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system. ...
s in the skin.
Conditions included in this groups are:
* Cutaneous lymphoid hyperplasia with nodular pattern, a condition of the skin characterized by a solitary or localized cluster of asymptomatic
erythematous
Erythema (from the Greek , meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. It occurs with any skin injury, infection, or inflammation. Examples of erythema not assoc ...
to violaceous
papules or nodules
* Cutaneous lymphoid hyperplasia with bandlike and perivascular patterns, a condition of the skin characterized by
skin lesions that clinically resemble
mycosis fungoides
Jessner lymphocytic infiltrate
Jessner lymphocytic infiltrate of the skin is a cutaneous condition characterized by a persistent
papular
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the Human body, body and includes skin, Nail (anatomy), nails, and related muscle and glands. Th ...
and plaque-like skin eruption which can occur on the neck, face and back and may re-occur. This is an uncommon skin disease and is a benign collection of lymph cells. Its cause is not known and can be hereditary.
It is named for
Max Jessner. It is thought to be equivalent to
lupus erythematosus tumidus
Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Comm ...
.
It can occur as the result of
ACE inhibitors and a number of medications used to treat
multiple sclerosis
Multiple (cerebral) sclerosis (MS), also known as encephalomyelitis disseminata or disseminated sclerosis, is the most common demyelinating disease, in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This d ...
including
glatiramer acetate
Glatiramer acetate (also known as Copolymer 1, Cop-1), sold under the brand name Copaxone among others, is an immunomodulator medication used to treat multiple sclerosis. Glatiramer acetate is approved in the United States to reduce the frequency ...
.
See also
*
Lyme disease
*
Skin lesion
*
Tick bite
Ticks (order Ixodida) are parasitic arachnids that are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, species, and "fullness". Ticks are external parasites, living by ...
References
External links
Lymphoid-related cutaneous conditions
{{Cutaneous-condition-stub