Cloxestradiol (), also known as 17-(2,2,2-trichloroethoxy)estradiol, is a
synthetic Synthetic things are composed of multiple parts, often with the implication that they are artificial. In particular, 'synthetic' may refer to:
Science
* Synthetic chemical or compound, produced by the process of chemical synthesis
* Synthetic ...
,
steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and ...
al
estrogen
Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal ac ...
which was never marketed.
It is an
analogue of
estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development o ...
with a 2,2,2-trichloroethoxy substitution.
The ''O'',''O''-diacetate derivative,
cloxestradiol acetate
Cloxestradiol acetate (brand name Genovul), also known as 17-(2,2,2-trichloroethoxy)estradiol ''O'',''O''-diacetate, is a synthetic steroidal estrogen derived from estradiol. It is the ''O'',''O''-diacetate ester of cloxestradiol
Cloxestradiol ...
(brand name Genovul), has been marketed as an estrogen.
See also
*
List of estrogens
This is a list of steroidal estrogens or derivatives of estradiol, estrone, and estriol. Most esters of these estrogens are not included in this list; for esters, see here instead.
Estradiol derivatives
17α-Substituted estradiol derivative ...
*
List of estrogen esters
This is a list of estrogen esters, or ester prodrugs of estrogens. It includes esters, as well as ethers, of steroidal estrogens like estradiol, estrone, and estriol and of nonsteroidal estrogens like the stilbestrols diethylstilbestrol and hex ...
References
Abandoned drugs
Sterols
Phenols
Estranes
Estrogen ethers
Synthetic estrogens
Trichloromethyl compounds
{{Steroid-stub