Clavaviridae
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''Clavaviridae'' is a family of double-stranded viruses that infect archaea. This family was first described by the team led by D. Prangishvili in 2010. There is one genus in this family (''Clavavirus''). Within this genus, a single species has been described to date: '' Aeropyrum pernix bacilliform virus 1'' (APBV1). The name is derived from the
Latin Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the ...
word ''clava'' meaning stick.


Virology

The virons are bacilliform in shape and 143 nanometers (nm) in length and 15.8 nm in diameter. One end is pointed and the other is rounded. The structure of the APBV1 virion has been solved by cryo-electron microscopy to near-atomic resolution, revealing how the helical particle is built from an alpha-helical major capsid protein with a unique structural fold. Virions are highly thermostable and remain infectious after incubation at 100 °C for 3 h The genome is a circular double-stranded DNA molecule of 5.3 kb. It does not integrate into the host genome. The genome contains 14 open reading frames, none of which share similarity with sequences in public databases. Infection with this virus does not cause host cell lysis.


References


External links


ICTV Report: ''Clavaviridae'
Double-stranded DNA viruses Virus families {{virus-stub