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The Christie NHS Foundation Trust is located in Withington, Manchester, and is one of the largest cancer treatment centres in Europe. The Christie became a NHS Foundation Trust in April 2007 and is also an international leader in cancer research and development, and home to the Paterson Institute for Cancer
Cancer
Research.

Contents

1 History

1.1 Foundation of the Christie Hospital 1.2 Foundation of the Holt Institute 1.3 The Christie at Withington 1.4 Cancer
Cancer
Research UK Manchester
Manchester
Institute (former Paterson Institute for Cancer
Cancer
Research)

2 Services

2.1 Private patients

3 Foundation Trust 4 Performance 5 Fire incident 6 See also 7 References 8 External links

History[edit] Foundation of the Christie Hospital[edit] The hospital had its beginnings in the largesse of Sir Joseph Whitworth, a wealthy Mancunian inventor who left money in his will in 1887. He wanted this to be spent on good causes in Manchester
Manchester
and entrusted his bequest to three legatees, one of whom was Richard Copley Christie.[1] Consequently, some of that money was used to buy land off Oxford Road, adjacent to Owens College
Owens College
and intended to allow the movement of the central Manchester
Manchester
hospitals out of the crowded city centre.[2] A committee chaired by Christie was established in 1890 and, partly funded by a legacy of £10,000 from Daniel Proctor, a Cancer
Cancer
Pavilion and Home for Incurables was founded on the site in 1892 some distance south-east of the eye hospital.[3] In 1901 it was renamed the Christie Hospital in honour of Richard Christie and his wife Mary.[4] It was the only hospital outside London for the treatment of cancer alone and active in pathological research.[5] Foundation of the Holt Institute[edit] In 1901, the Christie Management Committee agreed to the request of Dr Robert Biggs Wild to spend £50 on the equipment necessary to test the efficacy of X ray
X ray
treatment, after promising results reported from London and from three patients treated in the Physics Laboratory of Professor Schuster locally in Owens College. The Roentgen apparatus was purchased, but no records survive of treatment, and by 1907 the equipment was no longer being used (it was given to the Skin Hospital in 1910).[6] By 1905, Dr Wild had become interested in the therapeutic use of the newly discovered radium and experimented, once more with aid from Professor Schuster, on three patients. Radium
Radium
was expensive, however, and the management refused to purchase any more until the results of tests from London hospitals were available. By 1914, a leading local doctor, Sir William Milligan, had begun a campaign in the ' Manchester
Manchester
Guardian' to raise funds for radium treatment. Appealing to a mixture of local pride and the contemporary enthusiasm for the curative powers of radium, an appeal was launched, on the advice of Ernest Rutherford, for £25,000. An initial contribution of £2000 from local brewer Edward Holt was not initially much emulated, but following the intervention of the Mayor, a series of ' Radium
Radium
days' were organized which eventually raised enough money to start a small Radium
Radium
Institute, initially housed in the Manchester
Manchester
Royal Infirmary. In 1921 it moved to new premises in Nelson Street donated by Sir Edward and Lady Holt, and became the Manchester
Manchester
and District Radium Institute.[6] By contrast with the dispersed and competitive provision of London radiotherapy, Manchester
Manchester
became the first provider of a centralised radiotherapy service, which would have long-lasting effects on the patterns of British cancer care.[7][8] The Christie at Withington[edit] In 1932 the Institute, renamed as the Holt Radium
Radium
Institute, and the Christie Hospital moved to a new joint site in Withington
Withington
and began to be jointly managed although a formal merger did not occur until 1946.[6] Ralston Paterson was appointed as Director of the Radium
Radium
Institute in 1931, and went on to build a world recognised centre for the treatment of cancer by radiation.[8] Among the team was his wife Edith Paterson, who started research work at the Christie in 1938, initially unpaid, and who became a world-renowned pioneer in biological dosimetry, childhood cancers and anti-cancer drug treatment methods.[citation needed] After Ralston Paterson's retirement in 1963, Professor Eric Craig Easson, CBE, was appointed Director of the Christie Hospital. He became world famous for his contribution to the curability of Hodgkin's disease and to cancer education. He was awarded a personal Professorial Chair at the University of Manchester, and was President of the Royal College of Radiologists (1975–1977). He was the government adviser on cancer for many years, and was a prime mover in the Union Internationale Contre Cancer
Cancer
in Geneva, as well as the WHO cancer group. During Professor Easson's tenure as Director, many doctors from throughout the world visited the Christie Hospital to absorb its ethos, but particularly to learn its techniques. Early impetuses to research came from new local diseases of industrialisation such as mule spinners' cancer and chimney sweep's cancer, and the search for links to machine oils and airborne soot. Subsequent therapeutic milestones have included:[4]

1932 - development of the Manchester
Manchester
Method, the first international standard for radium treatment 1944 - world's first clinical trial of diethylstilbestrol (Stilboestrol) for breast cancer 1970 - world's first clinical use of tamoxifen (Nolvadex) for breast cancer 1986 - world's first use of cultured bone marrow for leukaemia treatment 1991 - world's first single harvest blood stem-cell transplant

Cancer
Cancer
Research UK Manchester
Manchester
Institute (former Paterson Institute for Cancer
Cancer
Research)[edit] Professor Laszlo Lajtha was appointed director of research in 1962. New research laboratories, provided by the Women's Trust Fund and named after the Patersons, were opened in 1966. The Women's Trust Fund was a local charity, chaired by Lady Margaret Holt, daughter-in-law of Sir Edward Holt, who left her entire estate of over £8 million to the Christie when she died in 1997.[3] Core funding for the laboratories was secured from the Medical Research Council and the Cancer
Cancer
Research Campaign (CRC). The CRC also located the CRC Department of Medical Oncology, led by Professor Derek Crowther, at the Paterson.[9] Lajtha was succeeded as Director in 1983 by Professor David Harnden. Professor T. Michael Dexter served in the post for a short time before the appointment of Professor Nic Jones as Director in March 1999. [9] Professor Jones stepped down in 2011 and Professor Richard Marais was appointed as the new Director in 2012. [10]" Cancer
Cancer
Research UK Manchester
Manchester
Institute History". Retrieved 2017-03-31.  The Paterson Institute for Cancer
Cancer
Research changed its name to the Cancer
Cancer
Research UK Manchester
Manchester
Institute on 1 October 2013. Services[edit] The Christie registers around 12,500 new patients and treats about 40,000 patients every year. It is the lead cancer centre for the Greater Manchester
Manchester
and Cheshire Cancer
Cancer
Network, covering a population of 3.2 million, and runs clinics at 16 other general hospitals.[11] Around 15% of patients are referred from outside Greater Manchester and Cheshire, and there is also a private patients unit. Patients are referred from district general hospitals, having already had their cancer diagnosed. The Christie is the largest cancer treatment centre of its kind in Europe and an international leader in research and development. As of 2010 the Christie is home to the largest clinical trials unit of its kind in Europe. The Christie annually delivers over 30,000 chemotherapy treatments and undertakes around 3,700 operations every year. It has one of the eight dedicated teenage cancer units in the United Kingdom. It has 257 inpatient beds with an average length of stay of seven days.[11] The hospital has one of the largest clinical trials units in the United Kingdom for phase I/II cancer trials, with around 1,200 patients going on new trials, with plans to double over the next few years to be one of largest clinical trials units in the world.[11] It is a partner in the Manchester
Manchester
Cancer
Cancer
Research Centre and home to the North West Cancer
Cancer
Information Service, the cancer registry for the whole of the North West region, and the Wolfson Molecular Imaging Centre. Private patients[edit] HCA Healthcare
HCA Healthcare
has run a specialist private cancer unit in partnership with the trust since 2010. [12] Foundation Trust[edit] The Christie became a NHS Foundation Trust on 1 April 2007. It has a total annual turnover of around £143 million. Eight percent of its income is from private patients. Around 2,000 staff and over 300 volunteers work at the Christie.[11] The first Chair of the Trust was Jim Martin. He was replaced in May 2011 by Lord Keith Bradley [13] Caroline Shaw, the chief executive of the trust, was suspended from her duties on 19 December 2013 while investigations were conducted as part of a disciplinary process. It was alleged that she had made an improper claim for the payment of expenses for a retreat in Ibiza organised by the Young Presidents' Organization, of which she had become a member with the Trust’s agreement.[14] In February 2014 Lord Bradley announced that he would resign from the board as a consequences of disagreements about the way in which the suspension of the Chief Executive was being handled.[15] Sir Hugh Taylor was appointed as interim Chair of the Trust. Shaw resigned in October 2014, having been suspended on full pay for 11 months- amounting to £170,000 and left with another six months salary - just under £100,000.[16] Dr Kim Holt, chair of the patient safety campaign group Patients First, demanded an independent investigation into claims of bullying, intimidation and dismissal of whistleblowers at the Trust in March 2014.[17] A report was conducted by Monitor (NHS) and the CQC which concluded there was no evidence of serious failings of governance or widespread cultural issues at the trust.[18] Performance[edit] It was named by the Health Service Journal
Health Service Journal
as one of the top hundred NHS trusts to work for in 2015. At that time it had 2,313 full-time equivalent staff and a sickness absence rate of 3.41%. 92% of staff recommend it as a place for treatment and 73% recommended it as a place to work.[19] The Care Quality Commission
Care Quality Commission
rated it as outstanding in 2016.[20] Fire incident[edit] On Wednesday 26 April 2017 at 10:36am, the fire service was called to a building fire within the Cancer
Cancer
Research UK Manchester
Manchester
Institute at Christie Hospital, it is believed that a blaze had broke out within the roof, where maintenance had been done on the roof a week before the blaze. The blaze involved five fire fighters, and an aerial ladder. [21] At 11:52am, the fire brigade had been praised by cancer experts for saving 25 years of vital research from the blaze. [22] See also[edit]

Healthcare in Greater Manchester List of hospitals in England List of NHS trusts Cancer
Cancer
in the United Kingdom

References[edit]

^ "Christie, Richard Copley (DNB01)". Dictionary of National Biography (1901). 1901. Retrieved 2012-10-30.  ^ " Manchester
Manchester
Medical Collection: Hospitals and related institutions in the Manchester
Manchester
area". Archived from the original on 22 December 2012. Retrieved 20 December 2007.  ^ a b "Press Release - 13th May 2004". Archived from the original on 27 May 2007. Retrieved 20 December 2007.  ^ a b "History of the Hospital". Archived from the original on 28 September 2007. Retrieved 6 December 2007.  ^ British Medical Association (ed.) (1929) The Book of Manchester
Manchester
and Salford: for the 97th annual meeting. Manchester: George Falkner & Sons ^ a b c Fox BW (1998). "The history of radium in medicine in Manchester". Clin Oncol (R Coll Radiol). 10 (2): 115–24. PMID 9610901.  ^ Ronald W. Raven. (1990). The Theory and Practice of Oncology. Informa Healthcare. ISBN 1-85070-179-2.  ^ a b Pickstone JV (2007). "Contested cumulations: configurations of cancer treatments through the 20th century". Bull Hist Med. 81 (1): 164–96. doi:10.1353/bhm.2007.0011. PMC 2635842 . PMID 17369667.  ^ a b "Paterson Institute for Cancer
Cancer
Research - History of the Institute". Archived from the original on 2007-08-13. Retrieved 2007-12-20.  ^ Cite error: The named reference Cancer
Cancer
Research UK Manchester Institute History was invoked but never defined (see the help page). ^ a b c d "About the Christie". Archived from the original on 1 July 2007. Retrieved 6 December 2007.  ^ "NHS expands private care to help fill £20bn funding gap". Financial Times. 2 March 2016. Retrieved 26 January 2017.  ^ Keith, Bradley. "Christie appoints new chairman". Archived from the original on 29 October 2013. Retrieved 27 October 2013.  ^ "The Christie hospital chief executive Caroline Shaw suspended". Manchester
Manchester
Evening News. 19 December 2013. Retrieved 20 December 2013.  ^ "Christie hospital chairman Lord Bradley to resign". Manchester Evening News. 28 February 2014. Retrieved 10 March 2014.  ^ "Boss of The Christie resigns after investigation into Ibiza trip". Manchester
Manchester
Evening News. 10 October 2014. Retrieved 10 October 2014.  ^ "Call for investigation into 'bullying' at cancer trust". Health Service JOurnal. 3 March 2014. Retrieved 14 March 2014.  ^ "Health watchdog says The Christie needs to develop 'open culture' for staff to raise concerns". Manchester
Manchester
Evening News. 27 November 2014. Retrieved 23 December 2014.  ^ "HSJ reveals the best places to work in 2015". Health Service Journal. 7 July 2015. Retrieved 23 September 2015.  ^ " Cancer
Cancer
hospital The Christie rated as 'outstanding'". BBC News. 18 November 2016. Retrieved 18 January 2017.  ^ "Fire breaks out at Manchester
Manchester
Christie hospital building". The Telegraph. 26 April 2017. Retrieved 26 April 2017.  ^ "Fire at Christie hospital cancer research labs". ITV News. 26 April 2017. Retrieved 26 April 2017. 

External links[edit]

The Christie NHS Foundation Trust homepage About the Hospital History of the Hospital The Paterson Institute for Cancer
Cancer
Research The Wolfson Molecular Imaging Centre

Coordinates: 53°25′47″N 2°13′43″W / 53.42972°N 2.22861°W /

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