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A chloride channel opener is a type of
A chloride channel opener is a type of drug
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...
which facilitates ion
An ion () is an atom or molecule with a net electrical charge.
The charge of an electron is considered to be negative by convention and this charge is equal and opposite to the charge of a proton, which is considered to be positive by conven ...
transmission through chloride channels.
An example is 1,10-phenanthroline
1,10-Phenanthroline (phen) is a heterocyclic organic compound. It is a white solid that is soluble in organic solvents. The 1,10 refer to the location of the nitrogen atoms that replace CH's in the hydrocarbon called phenanthrene.
Abbreviated ...
, which activates Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels.
GABA-A receptor agonists (e.g. lorazepam
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. It is used to treat anxiety disorders, trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and c ...
) may also be considered chloride channel openers
See also
*Chloride channel blocker A chloride channel blocker is a type of drug which inhibits the transmission of ions (Cl−) through chloride channels.
Niflumic acid is a chloride channel blocker that has been used in experimental scientific research. Another example is anthrace ...
References
Further reading
* * Ion channel openers Membrane transport modulators {{pharmacology-stub