Cefsulodin is a third-generation cephalosporin antibiotic that is active against ''

Pseudomonas aeruginosa ''Pseudomonas aeruginosa'' is a common encapsulated, gram-negative, aerobic–facultatively anaerobic, rod-shaped bacterium that can cause disease in plants and animals, including humans. A species of considerable medical importance, ''P. aerug ...

'' and was discovered by

Takeda Pharmaceutical Company The is a Japanese multinational pharmaceutical company, with partial American and British roots. It is the largest pharmaceutical company in Asia and one of the top 20 largest pharmaceutical companies in the world by revenue (top 10 followin ...

in 1977.

TAP Pharmaceuticals TAP Pharmaceuticals was formed in 1977 as a joint venture between the two global pharmaceutical companies, Abbott Laboratories and Takeda Pharmaceutical Co. and was dissolved in 2008; its two most lucrative products were proton-pump inhibitor lan ...

had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985. Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for ''Yersinia'' microorganisms. This agar is most often used in water and beverage testing.

Susceptibility data

The following represents MIC susceptibility data for various ''P. aeruginosa'' strains: * ''Pseudomonas aeruginosa'' PA13 (resistant strain): 32 μg/ml * ''Pseudomonas aeruginosa'' (wild-type, susceptible): 4 - 8 μg/ml

References

{{CephalosporinAntiBiotics Cephalosporin antibiotics Isonicotinamides Takeda Pharmaceutical Company brands Sulfonates