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The medication
paracetamol Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior ...
(
INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...
) ( or ), also known as acetaminophen (
USAN 280px, "Samguk Sagi" Book 04. Silla's Records. In 512, Usan-guk(于山國)was Ulleungdo(鬱陵島) Usan-guk, or the State of Usan, occupied Ulleung-do and the adjacent islands during the Korean Three Kingdoms period. According to th ...
) , is sold around the world under a number of different brand names. Common brand names include
Tylenol Tylenol may refer to: * Paracetamol (acetaminophen), a medication used to treat pain and fever * Tylenol (brand) Tylenol () is a brand of medication, advertised for reducing pain, reducing fever, and relieving the symptoms of allergies, cold, ...
,
Excedrin Aspirin(acetylsalicylic acid) / paracetamol(acetaminophen) / caffeine is a combination drug for the treatment of pain, especially tension headache and migraine. It is sold in the US under the trade names Goody's Powder and Excedrin, although no ...
, Calpol, and Panadol.


Tylenol

Tylenol is a
brand A brand is a name, term, design, symbol or any other feature that distinguishes one seller's good or service from those of other sellers. Brands are used in business, marketing, and advertising for recognition and, importantly, to create an ...
of
drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...
s advertised for reducing
pain Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, ...
, reducing
fever Fever, also referred to as pyrexia, is defined as having a body temperature, temperature above the human body temperature, normal range due to an increase in the body's temperature Human body temperature#Fever, set point. There is not a single ...
, and relieving the symptoms of
allergies Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
,
cold Cold is the presence of low temperature, especially in the atmosphere. In common usage, cold is often a subjective perception. A lower bound to temperature is absolute zero, defined as 0.00K on the Kelvin scale, an absolute thermodynamic ...
,
cough A cough is a sudden expulsion of air through the large breathing passages that can help clear them of fluids, irritants, foreign particles and microbes. As a protective reflex, coughing can be repetitive with the cough reflex following three pha ...
headache, and
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms ...
. The active ingredient of its original flagship product is
paracetamol Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior ...
. The brand name "Tylenol" is owned by
McNeil Consumer Healthcare McNeil Consumer Healthcare is an American medicals products company belonging to the Johnson & Johnson Health care, healthcare products group. It primarily sells fast-moving consumer goods such as Over-the-counter drug, over-the-counter drugs. ...
, a subsidiary of
Johnson & Johnson Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company i ...
. As of 2017 the brand was used in Brazil, Canada, China, Egypt, Lebanon, Myanmar, Oman, Philippines, Portugal, Switzerland, Thailand, United States, and Vietnam.


Calpol

Calpol is a brand of children's medicine sold in the UK,
Ireland Ireland ( ; ga, Éire ; Ulster Scots dialect, Ulster-Scots: ) is an island in the Atlantic Ocean, North Atlantic Ocean, in Northwestern Europe, north-western Europe. It is separated from Great Britain to its east by the North Channel (Grea ...
,
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
,
Cyprus Cyprus ; tr, Kıbrıs (), officially the Republic of Cyprus,, , lit: Republic of Cyprus is an island country located south of the Anatolian Peninsula in the eastern Mediterranean Sea. Its continental position is disputed; while it is geo ...
,
Hong Kong Hong Kong ( (US) or (UK); , ), officially the Hong Kong Special Administrative Region of the People's Republic of China ( abbr. Hong Kong SAR or HKSAR), is a city and special administrative region of China on the eastern Pearl River Delt ...
,
Kenya ) , national_anthem = "Ee Mungu Nguvu Yetu"() , image_map = , map_caption = , image_map2 = , capital = Nairobi , coordinates = , largest_city = Nairobi , ...
,
Malta Malta ( , , ), officially the Republic of Malta ( mt, Repubblika ta' Malta ), is an island country in the Mediterranean Sea. It consists of an archipelago, between Italy and Libya, and is often considered a part of Southern Europe. It lies ...
and the
Philippines The Philippines (; fil, Pilipinas, links=no), officially the Republic of the Philippines ( fil, Republika ng Pilipinas, links=no), * bik, Republika kan Filipinas * ceb, Republika sa Pilipinas * cbk, República de Filipinas * hil, Republ ...
. The main product is a
paracetamol Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior ...
suspension, branded as ''Calpol Infant Suspension''. It is usually a coloured
syrup In cooking, a syrup (less commonly sirup; from ar, شراب; , beverage, wine and la, sirupus) is a condiment that is a thick, viscous liquid consisting primarily of a solution of sugar in water, containing a large amount of dissolved sugars ...
with a sweet taste, and is used to treat fever and pain. In 2016 it was the second biggest selling branded over-the-counter medication sold in Great Britain, with sales of £66.3 million. Calpol also comes in a form containing
ibuprofen Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. It may also be used to close a patent ductus arte ...
, marketed under the name Calprofen. Calpol is a common cause of accidental child poisoning because of its pleasant taste. Calpol Night, a product containing paracetamol and an anti-histamine, was listed for use from 2+ months. However, this was changed and it is now only considered suitable for children over the age of 6 years.


History

Calpol was launched in 1959 by English pharmaceutical company, Calmic Ltd, based in
Crewe Crewe () is a railway town and civil parish in the unitary authority of Cheshire East in Cheshire, England. The Crewe built-up area had a total population of 75,556 in 2011, which also covers parts of the adjacent civil parishes of Willaston ...
,
Cheshire Cheshire ( ) is a ceremonial and historic county in North West England, bordered by Wales to the west, Merseyside and Greater Manchester to the north, Derbyshire to the east, and Staffordshire and Shropshire to the south. Cheshire's county t ...
; the company's name was an abbreviation of Cheshire and Lancashire Medical Industries Corporation, which moved from Lancashire to
Crewe Hall Crewe Hall is a Jacobean mansion located near Crewe Green, east of Crewe, in Cheshire, England. Described by Nikolaus Pevsner as one of the two finest Jacobean houses in Cheshire,Pevsner & Hubbard, p. 22 it is listed at grade I. Built in 16 ...
in 1947. The Calpol brand name is likely a combination of 'Calmic' and 'paracetamol'. Calmic was acquired by Wellcome (today
GlaxoSmithKline GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the ten ...
) in 1966, and Calpol became one of Wellcome's best-selling UK products in the 1980s. The brand was later owned by
Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...
Consumer Healthcare, which was acquired by
Johnson & Johnson Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company i ...
in 2006. Calpol is today a brand of Johnson & Johnson's
McNeil Consumer Healthcare McNeil Consumer Healthcare is an American medicals products company belonging to the Johnson & Johnson Health care, healthcare products group. It primarily sells fast-moving consumer goods such as Over-the-counter drug, over-the-counter drugs. ...
subsidiary; in 2020, Calpol was the UK's top-selling paediatric
analgesic An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
product with sales worth £60.1 million.


Panadol

Panadol is one of
GlaxoSmithKline GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the ten ...
's
trade name A trade name, trading name, or business name, is a pseudonym used by companies that do not operate under their registered company name. The term for this type of alternative name is a "fictitious" business name. Registering the fictitious name w ...
s for paracetamol or acetaminophen. According to GlaxoSmithKline, Panadol is marketed in 85 countries, including Australia, Belgium, Brazil, Bulgaria, Chile, Finland, France, Greece, Honduras, Hong Kong, Indonesia, Ireland, Italy, Kenya, Korea, Lebanon, Malaysia, Netherlands, New Zealand, Nigeria, the Philippines, Peru, Puerto Rico, Pakistan, Romania, Saudi Arabia, Singapore, South Africa, Sri Lanka, Switzerland, Taiwan, Thailand, Trinidad and Tobago, Turkey, the United Arab Emirates, Egypt, The United Kingdom, Vietnam, Malta, Uruguay, North Korea and Oman.


History

After it was first introduced only in clinics in 1953, Panadol started its commercial business in 1955 by Phillips, Scott & Turner, which was acquired by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. It was advertised as being "gentle on the stomach", since other
analgesic An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
agents at the time contained
aspirin Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. Specific inflammatory conditions which aspirin is used to treat inc ...
, a known stomach irritant. In 1955, Panadol was introduced to hospitals in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...
. Panadol was originally available only by prescription in the UK, but is now available over the counter. In 1983, Sterling introduced Panadol to the United States market. In 1988
Sterling Winthrop Sterling Drug was an American global pharmaceutical company, also known as Sterling Winthrop, Inc. in its last years (after the merger with Winthrop-Stearns Inc. which itself resulted from the merger of ''Winthrop Chemical Company Inc.'' and '' ...
was acquired by
Eastman Kodak The Eastman Kodak Company (referred to simply as Kodak ) is an American public company that produces various products related to its historic basis in analogue photography. The company is headquartered in Rochester, New York, and is incorpor ...
which sold the worldwide over the counter drug business to
SmithKline Beecham GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tent ...
in 1994. Two weeks later, SmithKline Beecham sold the over-the-counter medication business in the United States, Canada and Puerto Rico to
Bayer Bayer AG (, commonly pronounced ; ) is a German multinational corporation, multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of busi ...
for US$1 billion. However, North American rights to Panadol were retained by SmithKline. It has been called "one of the most-frequently counterfeited medicines in the world."


Other formulations and packaging

Panadol is sold in different formulations and packaging with different names. ''Panadol Extra'', an S2 pharmacy-only medicine in Australia, combines 65 mg of
caffeine Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class. It is mainly used recreationally as a cognitive enhancer, increasing alertness and attentional performance. Caffeine acts by blocking binding of adenosine t ...
with 500 mg of paracetamol per tablet. Caffeine may improve the analgesic effect of paracetamol. Studies have reached conflicting conclusions regarding the clinical significance of this incremental pain relief. ''Panadol Osteo'' and ''Panadol Extend Tablets'' are modified-release formulations of paracetamol. ''Panadol Osteo'' is marketed in Australia and New Zealand; its immediate to sustained release ratio is 33% to 66%. ''Panadol Rapid Handipak'' is ''Panadol Rapid'' packaged in a slim container of ten 500 mg caplets, designed to appeal to Australian women who are 20 to 35 years of age. ''Panadol Cold and Catarrh'' contains three active ingredients: paracetamol, phenylephrine hydrochloride as a nasal decongestant, and chlorpheniramine maleate to prevent certain
allergies Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
. ''Panadol Cold and Flu'' and ''Panadol Fever and Congestion'' both combine paracetamol with phenylephrine hydrochloride as a nasal decongestant.


Other brand names


References

{{DEFAULTSORT:Paracetamol Brand Names, List Of Analgesics Antipyretics Lists of brands Phenols