CRL-40,941
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CRL-40,941 (also known as fladrafinil and fluorafinil) is a
eugeroic Eugeroics (originally "eugrégorique" or "eugregoric"), also known as wakefulness-promoting agents and wakefulness-promoting drugs, are a class of drugs that promote wakefulness and alertness. They are medically indicated for the treatment of cer ...
closely related to
adrafinil Adrafinil, sold under the brand name Olmifon, is a wakefulness-promoting medication that was formerly used in France to improve alertness, attention, wakefulness, and mood, particularly in the elderly. It was also used off-label by individuals w ...
and
modafinil Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. While it has seen off-label ...
. It is the bis(''p''-fluoro) ring-substituted derivative of adrafinil. CRL-40,941 was found to produce antiaggressive effects in animals, which adrafinil does not produce, and is purportedly 3 - 4 times stronger than adrafinil.


See also

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Adrafinil Adrafinil, sold under the brand name Olmifon, is a wakefulness-promoting medication that was formerly used in France to improve alertness, attention, wakefulness, and mood, particularly in the elderly. It was also used off-label by individuals w ...
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Armodafinil Armodafinil (trade name Nuvigil) is the enantiopure compound of the eugeroic modafinil (Provigil). It consists of only the (''R'')-(−)-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. an ...
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CRL-40,940 CRL-40,940 (also known as flmodafinil, bisfluoromodafinil and lauflumide) is the bisfluoro analog of modafinil. It is a eugeroic as well as a weak dopamine reuptake inhibitor. Its inventors claim that it is more effective than modafinil and adraf ...
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Fluorenol Fluorenol, also known as hydrafinil, is an Alcohol (chemistry), alcohol derivative of fluorene. In the most significant isomer, fluoren-9-ol or 9-hydroxyfluorene, the hydroxy group is located on the bridging carbon between the two benzene rings. H ...
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CE-123 CE-123 is an Structural analog, analog of modafinil, the most researched of a series of structurally related heterocyclic derivatives. In animal studies, CE-123 was found to improve performance on tests of learning and memory in a manner consiste ...


References

Abandoned drugs Benzene derivatives Designer drugs Drugs with unknown mechanisms of action Fluoroarenes Hydroxamic acids Prodrugs Stimulants Sulfoxides {{nervous-system-drug-stub