Butein is a

chalcone Chalcone is the organic compound C6H5C(O)CH=CHC6H5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids. Chemical properties Chalcones have two absorption maxima at ...

of the

chalconoid Chalconoids Greek: χαλκός ''khalkós'', " copper", due to its color), also known as ''chalcones'', are natural phenols related to chalcone. They form the central core for a variety of important biological compounds. They show antibacterial, ...

s. It can be found in ''

Toxicodendron vernicifluum ''Toxicodendron vernicifluum'' (formerly ''Rhus verniciflua''), also known by the common name Chinese lacquer tree, is an Asian tree species of genus '' Toxicodendron'' native to China and the Indian subcontinent, and cultivated in regions of ...

'' (or formerly ''Rhus verniciflua''), ''

Dahlia Dahlia (, ) is a genus of bushy, tuberous, herbaceous perennial plants native to Mexico and Central America. A member of the Asteraceae (former name: Compositae) family of dicotyledonous plants, its garden relatives thus include the sunflower, ...

'', ''

Butea ''Butea'' is a genus of flowering plants belonging to the pea family, Fabaceae. It is sometimes considered to have only two species, '' B. monosperma'' and '' B. superba'',Gwilym Lewis, Brian Schrire, Barbara MacKinder, and Mike Lock. 2005. '' ...

'' (''

Butea monosperma ''Butea monosperma'' is a species of ''Butea'' native to tropical and sub-tropical parts of the South Asia and Southeast Asia, ranging across Pakistan, India, Bangladesh, Nepal, Sri Lanka, Myanmar, Thailand, Laos, Cambodia, Vietnam, ...

'') and ''

Coreopsis ''Coreopsis'' () is a genus of flowering plants in the family Asteraceae. Common names include calliopsis and tickseed, a name shared with various other plants. Description These plants range from in height. The flowers are usually yellow wi ...

'' It has

antioxidative Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals. This can lead to polymerization and other chain reactions. They are frequently added to industrial products, such as fuels and lubricants, ...

aldose reductase In enzymology, aldose reductase (or aldehyde reductase) () is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides. It is primarily known for catalyzing the red ...

and advanced glycation endproducts inhibitory effects. It is also a

sirtuin-activating compound Sirtuin-activating compounds (STAC) are chemical compounds having an effect on sirtuins, a group of enzymes that use NAD+ to remove acetyl groups from proteins. They are caloric restriction mimetic compounds that may be helpful in treating various ...

, a chemical compound having an effect on sirtuins, a group of enzymes that use NAD⁺ to remove acetyl groups from proteins. Buteins possess a high ability to inhibit aromatase process in the human body, for this reason, the use of these compounds in the treatment of

breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or ...

on the estrogen ground has been explored. The first attempts of sport pro-hormone supplementation with the use of buteins took place in Poland.S.Amboziak
Aromatase in the dock"
09.2012

References

Chalconoids {{aromatic-stub