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The British National Formulary
British National Formulary
(BNF) is a United Kingdom
United Kingdom
(UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service
National Health Service
(NHS). Information within the BNF includes indication(s), contraindications, side effects, doses, legal classification, names and prices of available proprietary and generic formulations, and any other notable points.[1] Though it is a national formulary, it nevertheless also includes entries for some medicines which are not available under the NHS, and must be prescribed and/or purchased privately. A symbol clearly denotes such drugs in their entry. It is used by pharmacists and doctors (both general practitioners (GPs) and specialist practitioners), and by other prescribing healthcare professionals (such as nurses, pharmacy technicians, paramedics, and dentists); as a reference for correct dosage, indication, interactions and side effects of drugs. It is also used as a reassurance by those administering drugs, for example a nurse on a hospital ward, and even for patients and others seeking an authoritative source of advice on any aspect of pharmacotherapy. The British Pharmacopoeia (BP) specifies quality standards for the making of drugs listed in the BNF.

Contents

1 Development 2 History 3 Editions 4 Availability 5 Sister publications 6 BNF sections 7 See also 8 References 9 External links

Development[edit] Many individuals and organisations contribute towards the preparation of the BNF. It is jointly authored by the British Medical Association (BMA) and the Royal Pharmaceutical Society; and is jointly published by the BMJ Group (which is owned by the BMA), and the Pharmaceutical Press (owned by the Royal Pharmaceutical Society). It is published under the authority of a Joint Formulary Committee (JFC),[2] which comprises representatives of the two professional bodies, and the Department of Health (DoH). Information on drugs is drawn from the manufacturers' product literature, medical and pharmaceutical literature, regulatory authorities and professional bodies. Advice is constructed from clinical literature, and reflects, as far as possible, an evaluation of the evidence from diverse sources. The BNF also takes account of authoritative national guidelines and emerging safety concerns. In addition, the Joint Formulary Committee takes advice on all therapeutic areas from expert clinicians; this ensures that the BNF's recommendations are relevant to practice. However, in September 2013, the National Institute for Health and Care Excellence
National Institute for Health and Care Excellence
(NICE) in the UK opened a consultation on its draft decision not to give NICE accreditation to the processes to produce BNF publications following a review by an independent advisory committee.[3] History[edit] It was first published in 1949[2] as the National Formulary, with updated versions appearing every three years until 1976. The fifth version in 1957 saw its name change to The British National Formulary.[4][5] A new look version, under the auspices of Owen Wade, was released in 1981.[2][6] A study in Northern Ireland looking at prescribing in 1965, reported that the BNF was likely able to serve the requirements of prescribers in general practice, while also achieving a cost saving.[7] By 2003, issue 46 of the BNF contained 3000 interactions or groups of interactions, with about 900 of these marked by a bullet.[8] Editions[edit] A new edition of the BNF book is published twice-yearly; in March and September.[1] As of September 2017[update], the current edition is 74, which was published in September 2017. It is a customary tradition that the colour of each new edition is radically different from the previous.[2] Availability[edit] The BNF is presently available as a book, a website, and mobile applications - the latter for use on smartphones and tablets.[2] The book is available for purchase, and the September edition is distributed to healthcare professionals in the UK at no direct cost to them.[1][9] NHS workers and healthcare professionals in the HINARI group of developing nations are entitled to free access via MedicinesComplete following registration (requires provision of a name, an address, an email address, and a phone number). Other visitors can subscribe to the BNF on MedicinesComplete.[10] Healthcare organisations can also subscribe to a customisable BNF via their corporate online intranet.[11] In June 2012, the National Institute for Health and Care Excellence (NICE) released applications for offline access to the BNF on iOS and Android devices. An NHS Athens log-in is required to use this application, and monthly content updates are available, over an internet connection.[12] Sister publications[edit] The British National Formulary for Children
British National Formulary for Children
(BNFC)[1][13][14] book, first published September 2005,[2] is published yearly,[2] and details the doses and uses of medicines in children from neonates to adolescents.[1] The Nurse
Nurse
Prescriber's Formulary for Community Practitioners (NPF) is issued in print every two years (September, odd-numbered years), for use by District Nurses and Specialist Community Public Health Nurses (including Health Visitors) who have received training to become nurse prescribers.[1][15] BNF sections[edit] The British National Formulary
British National Formulary
is divided into various sections; with the main sections on drugs and preparations being organised by body system.

Table of Contents

Preface Acknowledgements How BNF publications are constructed How to use the BNF Changes Guidance on prescribing Prescription writing Emergency supply of medicines Controlled drugs and drug dependence Adverse reactions to drugs Guidance on intravenous infusions Prescribing for children Prescribing in hepatic impairment Prescribing in renal impairment Prescribing in pregnancy Prescribing in breast-feeding Prescribing in palliative care Prescribing for the elderly Drugs and sport Prescribing in dental practice

Notes on drugs and preparations

Gastro-intestinal system Cardiovascular system Respiratory system Nervous system Infection Endocrine system Genito-urinary system Malignant disease Blood and nutrition Musculoskeletal system Eye Ear, nose, and oropharynx Skin Vaccines Anaesthesia Emergency treatment of poisoning

Appendices and indices

Appendix 1 Interactions Appendix 2 Borderline substances Appendix 3 Cautionary and advisory labels for dispensed medicines Appendix 4 Wound management products and elasticated garments Dental Practitioners' Formulary Nurse
Nurse
Prescribers' Formulary Non-medical prescribing Index of proprietary manufacturers Special-order manufacturers

See also[edit]

Pharmacopeia Specification (technical standard)

References[edit]

^ a b c d e f "BNF Publications - Books". www.bnf.org. BMJ Group and Royal Pharmaceutical Society. Retrieved 16 August 2016.  ^ a b c d e f g "BNF Publications - About - Our organisation". www.bnf.org. BMJ Group and Royal Pharmaceutical Society. Retrieved 16 August 2016.  ^ "NICE seeks views to inform BNF accreditation decision". www.nice.org.uk (Press release). National Institute for Health and Care Excellence. 6 September 2013. Retrieved 19 July 2014.  ^ Anon (1957). "The British National Formulary". British Medical Journal). 2 (5047): 758–759. PMC 1962234 . PMID 13460381.  ^ Wade, O. L. (1993). "British National Formulary: Its birth, death, and rebirth". BMJ (Clinical research ed.). 306 (6884): 1051–1054. doi:10.1136/bmj.306.6884.1051. PMC 1676980 . PMID 8490505.  ^ Anon (1978). " British National Formulary
British National Formulary
1976-8". British Medical Journal). 2 (6136): 580–581. doi:10.1136/bmj.2.6136.580-b. PMC 1606955 . PMID 20792725.  ^ Wade, O. L.; McDevitt, G. D. (1966). "Prescribing and the british national formulary". British Medical Journal). 2 (5514): 635–637. doi:10.1136/bmj.2.5514.635. PMC 1943465 . PMID 20791099.  ^ Aronson, J. K. (2004). "Drug interactions-information, education, and the British National Formulary". British Journal of Clinical Pharmacology. 57 (4): 371–372. doi:10.1111/j.1365-2125.2004.02125.x. PMC 1884473 . PMID 15025733.  ^ "Archived copy". Archived from the original on 1 October 2012. Retrieved 2012-06-14.  ^ http://www.medicinescomplete.com/mc/ MedicinesComplete ^ http://www.bnfformularycomplete.com BNF on FormularyComplete ^ "NICE apps for smartphones and tablets". www.nice.org.uk. National Institute for Health and Care Excellence. April 2014. Retrieved 19 July 2014.  ^ Elias-Jones, A.; Rylance, G. (2005). "The launch of the British National Formulary for Children". Archives of Disease in Childhood. 90 (10): 997–998. doi:10.1136/adc.2005.080366. PMC 1720111 . PMID 16177154.  ^ "Archived copy". Archived from the original on 20 December 2007. Retrieved 2006-09-07.  British National Formulary
British National Formulary
for Children ^ "Products: Nurse
Nurse
Prescribers' Formulary". www.bnf.org. Retrieved 19 July 2014. 

External links[edit]

Official website

v t e

Pharmaceutical and biotechnology industry in the United Kingdom

Manufacturing in the United Kingdom Economy of the United Kingdom

companies

current

AAH Pharmaceuticals Alliance Boots Astex AstraZeneca
AstraZeneca
(MedImmune) BTG Cyclacel Dechra Pharmaceuticals GE Healthcare Genus GlaxoSmithKline Hikma Pharmaceuticals Indivior MacFarlan Smith Norbrook Group Oxford BioMedica Pfizer UK Phytopharm Proximagen Shire Silence Therapeutics TBS GB Unipath Vectura Group Vernalis ViiV Healthcare

defunct

Allen & Hanburys Amersham Beecham Group Cambridge Antibody Technology Celltech Chiroscience Distillers Company Fisons Glaxo Wellcome ICI Reliant Pharmaceuticals Renovo Zeneca

government and regulatory bodies

Commission on Human Medicines Department of Health European Directorate for the Quality of Medicines European Medicines Agency Medicines and Healthcare Products Regulatory Agency National Collaborating Centre for Mental Health National Patient Safety Agency Pharmaceutical Price Regulation Scheme Pharmaceutical Society of Northern Ireland General Pharmaceutical Council Scottish Medicines Consortium Veterinary Medicines Directorate

industry and professional bodies

Association of the British Pharmaceutical Industry Chemical Industries Association European Federation of Biotechnology European Federation of Pharmaceutical Industries and Associations Faculty of Pharmaceutical Medicine Pharmacists' Defence Association Royal Pharmaceutical Society
Royal Pharmaceutical Society
of Great Britain Worshipful Society of Apothecaries

books and journals

Bandolier Bad Pharma
Bad Pharma
(2012) British National Formulary British National Formulary
British National Formulary
for Children Monthly Index of Medical Specialities Side Effects (2008) The Pharmaceutical Journal

other

British Approved Name British Pharmacopoeia DrugScope European and Developing Countries Clinical Trials Partnership European Pharmacopoeia List of world's largest pharmaceutical companies Pharmaceutical Services Negotiating Committee Wellcome Tru

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