Bacillus thuringiensis israelensis
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''Bacillus thuringiensis'' serotype ''israelensis'' (Bti) is a group of bacteria used as biological control agents for larvae stages of certain dipterans. Bti produces toxins which are effective in killing various species of mosquitoes, fungus gnats, and blackflies, while having almost no effect on other organisms. The major advantage of '' B. thuringiensis'' products is that they are thought to affect few non-target species. However, even though Bti may have minimal direct effects on non-target organisms, it may potentially be associated with knock-on effects on
food webs A food web is the natural interconnection of food chains and a graphical representation of what-eats-what in an ecological community. Another name for food web is consumer-resource system. Ecologists can broadly lump all life forms into one ...
and other ecosystem properties, including biodiversity and ecosystem functioning. Bti strains possess the pBtoxis plasmid which encodes numerous Cry (a
δ-endotoxin Delta endotoxins (δ-endotoxins) are pore-forming toxins produced by ''Bacillus thuringiensis'' species of bacteria. They are useful for their insecticidal action and are the primary toxin produced by Bt maize/corn. During spore formation t ...
) and Cyt toxins, including Cry4, Cry10, Cry11, Cyt1, and Cyt2. The crystal aggregation which these toxins form contains at least four major toxic components, but the extent to which each Cry and Cyt protein is represented is not known and likely to vary with strain and formulation. Both Cry and Cyt proteins are pore-forming toxins; they lyse midgut
epithelial cells Epithelium or epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. It is a thin, continuous, protective layer of compactly packed cells with a little intercellu ...
by inserting into the target
cell membrane The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (t ...
and forming pores. Commercial formulations include "Mosquito Dunks" and "Mosquito Bits". It is also available in bulk liquid or granular formulations for commercial and public agency use.


Long name

''Bacillus thuringiensis'' subspecies ''israelensis'' strain EG2215


See also

*
Malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. ...


References


External links


''Bacillus thuringiensis'' fact sheet

EPA Controlling Mosquitoes at the Larval Stage
thuringiensis israelensis Biological control agents of pest insects {{Bacilli-stub