BTS 74,398 is a centrally acting

stimulant Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and inv ...

drug which was developed for the treatment of Parkinson's disease. It inhibits the synaptic reuptake of

dopamine Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic compound, organic chemical of the catecholamine and phenethylamine families. Dopamine const ...

serotonin Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vas ...

and noradrenaline, making it a

triple reuptake inhibitor Triple is used in several contexts to mean "threefold" or a "treble": Sports * Triple (baseball), a three-base hit * A basketball three-point field goal * A figure skating jump with three rotations * In bowling terms, three strikes in a row * In ...

. It was effective in animal models of Parkinson's disease, but was unsuccessful in human trials.

References

Stimulants Chlorobenzenes Secondary amines Thioethers Ethyleneamines Cyclobutanes {{Amine-stub

See also

References