Atagabalin (PD-0200,390) is a drug developed by
Pfizer
Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...
and related to
gabapentin
Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. It is a first-line medication for the treatment of neuropathic pain caused by diabeti ...
, which similarly binds to the α
2δ
calcium channels (
1 and
2).
It was under development as a treatment for
insomnia
Insomnia, also known as sleeplessness, is a sleep disorder in which people have trouble sleeping. They may have difficulty falling asleep, or staying asleep as long as desired. Insomnia is typically followed by daytime sleepiness, low energy, ...
,
but was discontinued following unsatisfactory trial results.
See also
*
4-Methylpregabalin
*
Gabapentin enacarbil
Gabapentin enacarbil (Horizant () (), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. It was designed for increased oral bioavailability over gabapentin, and human trials show ...
*
PD-217,014
References
Abandoned drugs
Amino acids
Calcium channel blockers
GABA analogues
Hypnotics
Pfizer brands
Cyclopentanes
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