Arylsulfatase (EC 3.1.6.1,
sulfatase
Sulfatases are enzymes of the esterase class that catalyze the hydrolysis of sulfate esters. These may be found on a range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amin ...
, nitrocatechol sulfatase, phenolsulfatase, phenylsulfatase, ''p''-nitrophenyl sulfatase, arylsulfohydrolase, 4-methylumbelliferyl sulfatase, estrogen sulfatase) is a type of
sulfatase
Sulfatases are enzymes of the esterase class that catalyze the hydrolysis of sulfate esters. These may be found on a range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amin ...
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''aryl-sulfate sulfohydrolase''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: an aryl sulfate + H
2O
a
phenol
Phenol (also called carbolic acid) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it req ...
+
sulfate
The sulfate or sulphate ion is a polyatomic anion with the empirical formula . Salts, acid derivatives, and peroxides of sulfate are widely used in industry. Sulfates occur widely in everyday life. Sulfates are salts of sulfuric acid and many ar ...
Types include:
*
Arylsulfatase A
Arylsulfatase A (or cerebroside-sulfatase) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate into cerebroside and sulfate. In humans, arylsulfatase A is encoded by the ''ARSA'' gene.
Pathology
A deficiency is associated with m ...
(also known as "cerebroside-sulfatase")
*
Arylsulfatase B
Arylsulfatase B (N-acetylgalactosamine-4-sulfatase, chondroitinsulfatase, chondroitinase, acetylgalactosamine 4-sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase, ) is an enzyme associated with mucopolysaccharidosis VI (Maroteaux–L ...
(also known as "''N''-acetylgalactosamine-4-sulfatase")
*
Steroid sulfatase
Steroid sulfatase (STS), or steryl-sulfatase (EC 3.1.6.2), formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the ''STS'' gene.
Reactions
This enzyme catalysis, catalyses the follow ...
(formerly known as "arylsulfatase C")
*
ARSC2
*
ARSD
*
ARSE
Arse or ARSE may refer to:
* A Commonwealth English slang term for the buttocks
* Arse, the name for the Iberian settlement of modern-day Sagunto
* Arse (district), a district in the South Tapanuli Regency, North Sumatra province, Sumatra, Indonesi ...
*
ARSF
*
ARSG
*
ARSH
*
ARSI
*
ARSJ
*
ARSK
Arsk ( rus, Арск, p=ˈarsk; tt-Cyrl, Арча, ''Arça'') is a town and the administrative center of Arsky District in the Tatarstan, Russia, located on the Kazanka River, from the republic's capital of Kazan. As of the 2010 Census, its p ...
See also
*
Aryl
In organic chemistry, an aryl is any functional group or substituent derived from an aromatic ring, usually an aromatic hydrocarbon, such as phenyl and naphthyl. "Aryl" is used for the sake of abbreviation or generalization, and "Ar" is used as ...
References
Hydrolases
EC 3.1.6
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