Arsenicin A is a naturally occurring organoarsenic chemistry, organoarsenic compound with molecular formula C₃H₆As₄O₃. It was first isolated from the New Caledonian marine sponge ''Echinochalina bargibanti''. The compound was characterized by Computational chemistry, computational and spectroscopy, spectroscopic techniques and found to possess a cage-like structure similar to adamantane in which the four methanetriyl carbon bridged compounds, bridgeheads are replaced by arsenic atoms and three of the six methylene bridges are replaced by oxygen atoms. It is the first polyarsenic compound ever found in nature. Subsequently, the proposed structure was prepared in large quantities via total synthesis and the structure was confirmed by x-ray crystallography. The molecule is Chirality, chiral, and has been resolved into its two Enantiomer, enantiomers. Arsenicin A is active against Promyelocytic leukemia, promelocytic leukemia cells at lower concentrations than the Arsenic trioxide, arsenic(III) oxide drug Trisenox.

References

{{reflist Organoarsenic compounds Arsenic heterocycles Oxygen heterocycles Adamantane-like molecules