Apramycin (also ''Nebramycin II'') is an aminoglycoside

antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...

used in veterinary medicine. It is produced by '' Streptomyces tenebrarius''.

Spectrum of bacterial susceptibility and resistance

Apramycin can be used to treat bacterial infections in animals caused by ''Escherichia coli, Klebsiella pneumoniae'', and ''Pseudomonas aeruginosa''. The following shows susceptibility data on medically significant organisms: * Escherichia coli - 1 μg/mL - >512 μg/mL (this large range may be due to resistant organisms, typical MIC values are likely in the range of 2 -8 μg/mL. * Klebsiella pneumoniae - 2 μg/mL - >256 μg/mL * Pseudomonas aeruginosa - 4 μg/mL

References

{{AminoglycosideAntiBiotics Aminoglycoside antibiotics