Products
Blisibimod
*Blisibimod is a selective peptibody antagonist of B-cell activating factor (BAFF). BAFF is critical to the development, maintenance and survival of B-cells, but is known to be up-regulated in autoimmune diseases. It is primarily expressed by macrophages, monocytes and dendritic cells. Blisibimod binds to BAFF and inhibits the interaction of BAFF with its receptors. Blisibimod is currently being evaluated in IgA nephropathy.Sollpura
July 2014, Anthera acquired Sollpura (Liprotamase) from Eli Lilly and Company. Sollpura is an investigational pancreatic enzyme replacement therapy (PERT) that uses three biotechnology-derived digestive enzymes intended to treat patients with endocrine pancreatic insufficiency as a result of cystic fibrosis and other diseases. Sollpura narrowly missed its target for Phase 3 of its clinical trials. It believes that specific conditions in the testing phase, specifically that patients were not able to increase dosages throughout the trial, negatively affected testing and led to the narrow shortcoming for Phase 3. It will conduct a new trial compensating for the perceived shortcoming at some point in the future.References
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