Activating Protein 2 (AP-2) is a family of closely related transcription factors[1][2] which plays a critical role in regulating gene expression during early development.[3]


  1. ^ Williams T, Tjian R (1991). "Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins". Science. 251 (4997): 1067–71. doi:10.1126/science.1998122. PMID 1998122. 
  2. ^ Williams T, Tjian R (1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". Genes Dev. 5 (4): 670–82. doi:10.1101/gad.5.4.670. PMID 2010091. 
  3. ^ Hilger-Eversheim K, Moser M, Schorle H, Buettner R (2000). "Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control". Gene. 260 (1-2): 1–12. doi:10.1016/S0378-1119(00)00454-6. PMID 11137286. 

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