Cyclic AMP-dependent transcription factor ATF-7 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''ATF7''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Homonym
In 2001, Peters et al. published a paper showing that ATF-7, a Novel bZIP Protein,
interacts with
PTP4A1.
This ATF-7 is actually
ATF5
Activating transcription factor 5, also known as ATF5, is a protein that, in humans, is encoded by the ''ATF5'' gene.
Function
First described by Nishizawa and Nagata, ATF5 has been classified as a member of the activating transcription factor ...
and not ATF7, as noted by the authors at the end of their paper ("Note Added in Proof—While this manuscript was under review, sequences for mouse and human ATF-5 were deposited in GenBankTM. It appears that ATF-7 and ATF-5 are likely to be the same protein. In addition, an unrelated sequence named ATF7 has also been deposited in GenBankTM. In order to avoid confusion, future work on the protein described in this publication will likely refer to it as either ATF-5 or ATF-5/7.")
References
Further reading
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External links
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Transcription factors
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