M01A
Anti-inflammatory Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as o ...
and antirheumatic products, non-steroids

M01AA Butylpyrazolidines

:M01AA01

Phenylbutazone Phenylbutazone, often referred to as "bute", is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals. In the United States and United Kingdom, it is no longer approved for human use (except in th ...

:M01AA02 Mofebutazone :M01AA03

Oxyphenbutazone Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID). It is a metabolite of phenylbutazone. It was withdrawn from markets worldwide in mid-1980s due to bone marrow suppression and the risk of Stevens–Johnson syndrome. The word "o ...

:M01AA05 Clofezone :M01AA06 Kebuzone :QM01AA90 Suxibuzone :QM01AA99 Combinations

M01AB Acetic acid derivatives and related substances

:M01AB01

Indometacin Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of pros ...

:M01AB02

Sulindac Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed as Clinoril. Imbaral (not to be confused with mebaral) is another name for this drug. Its name is derived from sul(finyl)+ ind(ene)+ ac(etic ...

:M01AB03 Tolmetin :M01AB04 Zomepirac :M01AB05

Diclofenac Diclofenac, sold under the brand name Voltaren, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. It is taken by mouth or rectally in a suppository, used by injection, or ...

:M01AB06 Alclofenac :M01AB07 Bumadizone :M01AB08

Etodolac Etodolac is a nonsteroidal anti-inflammatory drug (NSAID). It was patented in 1971 and approved for medical use in 1985. It was approved in the U.S. in 1991. Medical uses NSAIDs are used for the management of mild to moderate pain, fever, an ...

:M01AB09 Lonazolac :M01AB10 Fentiazac :M01AB11

Acemetacin Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in w ...

:M01AB12 Difenpiramide :M01AB13 Oxametacin :M01AB14

Proglumetacin Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a nonsteroidal anti-inflammatory drug (NSAID). It is metabolized in the body to indometacin and proglumide Proglumide (Milid) is a drug that inhibits ga ...

:M01AB15 Ketorolac :M01AB16 Aceclofenac :M01AB17 Bufexamac :M01AB51 Indometacin, combinations :M01AB55 Diclofenac, combinations

M01AC
Oxicam Oxicam is a class of non-steroidal anti-inflammatory drugs (NSAIDs), meaning that they have anti-inflammatory, analgesic, and antipyretic therapeutic effects. Oxicams bind closely to plasma proteins. Most oxicams are unselective inhibitors of the ...
s

:M01AC01

Piroxicam Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful inflammatory conditions like arthritis. Piroxicam works by preventing the production of endogenous prostaglandins which are in ...

:M01AC02 Tenoxicam :M01AC04 Droxicam :M01AC05

Lornoxicam Lornoxicam, also known as chlortenoxicam, is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral administration, ...

:M01AC06

Meloxicam Meloxicam, sold under the brand name Mobic among others, is a nonsteroidal anti-inflammatory medication (NSAID) used to treat pain and inflammation in rheumatic diseases and osteoarthritis. It is used by mouth or by injection into a vein. It i ...

:M01AC56 Meloxicam, combinations

M01AE Propionic acid derivatives

:M01AE01 Ibuprofen :M01AE02

Naproxen Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, gout and fever. It is taken orally. It is available in immediate and delayed release formulat ...

:M01AE03

Ketoprofen Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin. It was patented in 1967 and approved for medica ...

:M01AE04

Fenoprofen Fenoprofen is a nonsteroidal anti-inflammatory drug (NSAID). Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain. It has also been used to treat postoperative pain. Fenoprofen i ...

:M01AE05 Fenbufen :M01AE06 Benoxaprofen :M01AE07 Suprofen :M01AE08 Pirprofen :M01AE09

Flurbiprofen Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or de ...

:M01AE10

Indoprofen Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding. A 2004 study using high-throughput screening found indoprofen to increase produ ...

:M01AE11 Tiaprofenic acid :M01AE12

Oxaprozin Oxaprozin, also known as oxaprozinum, is a nonsteroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. Chemically, it is a propionic a ...

:M01AE13 Ibuproxam :M01AE14 Dexibuprofen :M01AE15

Flunoxaprofen Flunoxaprofen, also known as Priaxim, is a chiral nonsteroidal anti-inflammatory drug (NSAID). It is closely related to naproxen, which is also an NSAID. Flunoxaprofen has been shown to significantly improve the symptoms of osteoarthritis and rh ...

:M01AE16 Alminoprofen :M01AE17 Dexketoprofen :M01AE18 Naproxcinod :M01AE51 Ibuprofen, combinations :M01AE52 Naproxen and

esomeprazole Esomeprazole, sold under the brand name Nexium among others, is a medication which reduces stomach acid. It is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. Effectiveness is similar to ...

:M01AE53 Ketoprofen, combinations :M01AE56 Naproxen and

misoprostol Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat postpartum bleeding due to poor contraction of the uterus. Misoprostol is taken by mouth w ...

:QM01AE90 Vedaprofen :QM01AE91

Carprofen Carprofen is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that was previously for use in humans and animals, but is now only available to veterinarians for prescribing as a supportive treatment for various conditio ...

:QM01AE92 Tepoxalin

M01AG Fenamates

:M01AG01

Mefenamic acid Mefenamic acid is a member of the anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory drugs (NSAIDs), and is used to treat mild to moderate pain. Its name derives from its systematic name, dimethylphenylaminoben ...

:M01AG02 Tolfenamic acid :M01AG03

Flufenamic acid Flufenamic acid (FFA) is a member of the anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory drugs (NSAIDs). Like other members of the class, it is a cyclooxygenase (COX) inhibitor, preventing the formation of pr ...

:M01AG04

Meclofenamic acid Meclofenamic acid (used as meclofenamate sodium, brand name Meclomen) is a drug used for joint, muscular pain, arthritis and dysmenorrhea. It is a member of the anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory ...

:QM01AG90

Flunixin Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses, cattle and pigs. It is often formulated as the meglumine salt. In the United States, it is regulated by the U.S. Food and Drug Administration ( ...

M01AH Coxibs

:M01AH01

Celecoxib Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankyl ...

:M01AH02

Rofecoxib Rofecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It was marketed by Merck & Co. to treat osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, acute pain conditions, migraine, and dysmenorrhea. Rofecoxib ...

:M01AH03

Valdecoxib Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. It was patented in 1995. V ...

:M01AH04

Parecoxib Parecoxib, sold under the brand name Dynastat among others, is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor. It is injectable. It is approved through much of Europe for short term perioperative ...

:M01AH05

Etoricoxib Etoricoxib, sold under the trade name Arcoxia, is a selective COX-2 inhibitor from McOLSON Research Laboratories. Currently it is approved in more than 80 countries worldwide but not in the US, where the Food and Drug Administration (FDA) has r ...

:M01AH06 Lumiracoxib :M01AH07 Polmacoxib :QM01AH90 Firocoxib :QM01AH91 Robenacoxib :QM01AH92

Mavacoxib Mavacoxib (trade name Trocoxil) is a veterinary drug used to treat pain and inflammation in dogs with degenerative joint disease. It acts as a COX-2 inhibitor. Mavacoxib, along with other COX-2 selective inhibitors, celecoxib, valdecoxib, and p ...

:QM01AH93 Cimicoxib :QM01AH94 Deracoxib :QM01AH95 Enflicoxib

M01AX Other anti-inflammatory and antirheumatic agents, non-steroids

:M01AX01

Nabumetone Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID). Nabumetone was developed by Beecham and first received regulatory approval in 1991. It is available under numerous brand names, such as Relafen, Relifex, and Gambaran. Nabumetone is ...

:M01AX02

Niflumic acid Niflumic acid is a drug used for joint and muscular pain. It is categorized as an inhibitor of cyclooxygenase-2. In experimental biology, it has been employed to inhibit chloride channel Chloride channels are a superfamily of poorly understood ...

:M01AX04 Azapropazone :M01AX05

Glucosamine Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of two polysaccharides, chitosan and chitin. Glucosamine is one of the most ...

:M01AX07

Benzydamine Benzydamine (also known as Tantum Verde and branded in some countries as Maxtra Gargle, Difflam and Septabene), available as the hydrochloride salt, is a locally acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analg ...

:M01AX12 Glucosaminoglycan polysulfate :M01AX13 Proquazone :M01AX14 Orgotein :M01AX17

Nimesulide Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in ...

:M01AX18 Feprazone :M01AX21

Diacerein Diacerein ( INN), also known as diacetylrhein, is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints). It works by inhibiting interleukin-1 beta. An updated 2014 C ...

:M01AX22 Morniflumate :M01AX23 Tenidap :M01AX24 Oxaceprol :M01AX25

Chondroitin sulfate Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars ( N-acetylgalactosamine and glucuronic acid). It is usually found attached to proteins as part of a proteoglycan. A chondroitin chain can have ov ...

:M01AX26

Avocado The avocado (''Persea americana'') is a medium-sized, evergreen tree in the laurel family ( Lauraceae). It is native to the Americas and was first domesticated by Mesoamerican tribes more than 5,000 years ago. Then as now it was prized for ...

and

soybean oil Soybean oil (British English: soyabean oil) is a vegetable oil extracted from the seeds of the soybean (''Glycine max''). It is one of the most widely consumed cooking oils and the second most consumed vegetable oil. As a drying oil, processed s ...

, unsaponifiables :QM01AX52 Niflumic acid, combinations :M01AX68 Feprazone, combinations :QM01AX90

Pentosan polysulfate Pentosan polysulfate, sold under the brand name Elmiron among others, is a medication used for the treatment of interstitial cystitis. Zycosan, for horses, is a heparin-like compound and is the first injectable pentosan product to receive appro ...

:QM01AX91 Aminopropionitrile :QM01AX92 Grapiprant :QM01AX99 Combinations

M01B Anti-inflammatory/antirheumatic agents in combination

M01BA Anti-inflammatory/antirheumatic agents in combination with corticosteroids

:M01BA01 Phenylbutazone and corticosteroids :M01BA02 Dipyrocetyl and corticosteroids :M01BA03

Acetylsalicylic acid Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. Specific inflammatory conditions which aspirin is used to treat ...

and corticosteroids :QM01BA99 Combinations

M01BX Other anti-inflammatory/antirheumatic agents in combination with other drugs

M01C Specific antirheumatic agents

M01CA
Quinoline Quinoline is a heterocyclic aromatic organic compound with the chemical formula C9H7N. It is a colorless hygroscopic liquid with a strong odor. Aged samples, especially if exposed to light, become yellow and later brown. Quinoline is only sli ...
s

:M01CA03 Oxycinchophen

M01CB Gold preparations

:M01CB01

Sodium aurothiomalate Sodium aurothiomalate ( INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Along with an orally-administered gold salt, auranofin, it is one of only two ...

:M01CB02

Sodium aurothiosulfate Sodium aurothiosulfate, or sanocrysin, is the inorganic compound with the formula . This salt contains an anionic coordination complex of gold(I) bound to two thiosulfate ligands. It is colorless. History The compound was first synthesized in 18 ...

:M01CB03

Auranofin Auranofin is a gold salt classified by the World Health Organization as an antirheumatic agent. It has the brand name Ridaura. Use Auranofin is used to treat rheumatoid arthritis. It improves arthritis symptoms including painful or tender and ...

:M01CB04

Aurothioglucose Aurothioglucose, also known as gold thioglucose, is a chemical compound with the formula AuSC6H11O5. This derivative of the sugar glucose was formerly used to treat rheumatoid arthritis. History Throughout history, gold was used to cure diseases ...

:M01CB05 Aurotioprol

M01CC
Penicillamine Penicillamine, sold under the brand name of Cuprimine among others, is a medication primarily used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, ...
and similar agents

:M01CC01

Penicillamine Penicillamine, sold under the brand name of Cuprimine among others, is a medication primarily used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, ...

:M01CC02

Bucillamine Bucillamine is an antirheumatic agent developed from tiopronin. Activity is mediated by the two thiol In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other org ...

M01CX Other specific antirheumatic agents

References

{{Antirheumatic products M01 *