AMP—thymidine kinase
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In
enzymology Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, an AMP—thymidine kinase () is an enzyme that
catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the chemical reaction :AMP + thymidine \rightleftharpoons adenosine + thymidine 5'-phosphate Thus, the two substrates of this enzyme are AMP and thymidine, whereas its two products are
adenosine Adenosine ( symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9-glycosidic bond. Adenosine is one of the four nucleoside building ...
and thymidine 5'-phosphate. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (
phosphotransferase Phosphotransferases are a category of enzymes ( EC number 2.7) that catalyze phosphorylation reactions. The general form of the reactions they catalyze is: :A-P + B \rightleftharpoons B-P + A Where ''P'' is a phosphate group and A and B are the do ...
s) with an alcohol group as acceptor. The systematic name of this enzyme class is AMP:thymidine 5'-phosphotransferase. This enzyme is also called adenylate-nucleoside phosphotransferase.


References

* * EC 2.7.1 Enzymes of unknown structure {{2.7-enzyme-stub