A-68930 is a synthetic compound that acts as a selective

dopamine receptor Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through diffe ...

D₁ agonist. It is orally active and has antidepressant and

anorectic An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss. By contrast, an appetite stimulant is referred to as orexigenic. The term is (from the Greek ''ἀν-'' (an-) = "without" a ...

effects in animals, producing wakefulness and

tachycardia Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate. In general, a resting heart rate over 100 beats per minute is accepted as tachycardia in adults. Heart rates above the resting rate may be normal ( ...

, but without stimulant effects, instead producing sedation. The difference in effects between A-68930 and other D₁ agonists such as

SKF-82958 SKF-82,958 is a chemical synthesis, synthetic chemical compound, compound of the benzazepine chemical class, class that acts as a D1 receptor, D1/D5 receptor, D5 receptor full agonist. SKF-82,958 and similar D1-like-selective full agonists like S ...

may be due to their differing effects on the related D₅ receptor.

References

D1-receptor agonists Isochromenes Catechols Phenylethanolamine ethers {{Organic-compound-stub