8a-Phenyldecahydroquinoline (8A-PDHQ) is a high affinity NMDA antagonist developed by a team at Parke Davis in the 1950s. It is a structural analog of phencyclidine with slightly lower binding affinity than the parent compound. (-)-8a-Phenyldecahydroquinoline has an in vivo potency comparable to that of (+)- MK-801.

References

Arylcyclohexylamines Dissociative drugs NMDA receptor antagonists Quinolines Phenyl compounds {{hallucinogen-stub