5-Methoxy-''N'',''N''-diisopropyltryptamine (5-MeO-DiPT, sometimes called Foxy Methoxy or simply Foxy) is a
psychedelic tryptamine and the
methoxy
In organic chemistry, a methoxy group is the functional group consisting of a methyl group bound to oxygen. This alkoxy group has the formula .
On a benzene ring, the Hammett equation classifies a methoxy substituent at the ''para'' position a ...
derivative
In mathematics, the derivative of a function of a real variable measures the sensitivity to change of the function value (output value) with respect to a change in its argument (input value). Derivatives are a fundamental tool of calculus. ...
of
diisopropyltryptamine (DiPT).
Pharmacology
The mechanism that produces the purported hallucinogenic and entheogenic effects of 5-MeO-DiPT is thought to result primarily from
5-HT2A receptor agonism, although additional mechanisms of action such as
monoamine oxidase inhibition (MAOI) may be involved also.
The strongest receptor binding affinity for 5-MeO-DiPT is at the
5-HT1A receptor.
5-MeO-DiPT is
neurotoxic
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system. It occurs when exposure to a substance – specificall ...
in rats.
Overdose
Excessive doses have caused clinical intoxication, characterized by nausea, vomiting, agitation, hypotension, mydriasis, tachycardia and hallucinations, in a number of young adults. A number of these overdoses are attributed to the drug’s extended onset of action, where first time users, who were unfamiliar with the drug, administered a second dose after initially feeling no effects.
Rhabdomyolysis and renal failure occurred in one young man and another one died 3–4 hours after an apparent rectal overdose. At least one death has been attributed to consumption of 5-MeO-DiPT.
Drug prohibition laws
China
As of October 2015 5-MeO-DiPT is a controlled substance in China.
Denmark
Illegal since February 2004.
Germany
Illegal since September 1999.
Greece
Illegal since February 2003.
Japan
Illegal since April 2005.
Singapore
Illegal since early 2006.
Sweden
''Sveriges riksdags'' health ministry
''Statens folkhälsoinstitut'' classified 5-MeO-DiPT as "health hazard" under the act
''Lagen om förbud mot vissa hälsofarliga varor'' (translated ''Act on the Prohibition of Certain Goods Dangerous to Health'') as of Oct 1, 2004, in their regulation SFS 2004:696 listed as 5-metoxi-N,N-diisopropyltryptamin (5-MeO-DIPT), making it illegal to sell or possess.
United States
On April 4, 2003, the
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territori ...
DEA
The Drug Enforcement Administration (DEA; ) is a United States federal law enforcement agency under the U.S. Department of Justice tasked with combating drug trafficking and distribution within the U.S. It is the lead agency for domestic en ...
added both 5-MeO-DiPT and
alpha-methyltryptamine (AMT) to Schedule I of the
Controlled Substances Act under "emergency scheduling" procedures. The drugs were officially placed into Schedule I on September 29, 2004. Prior to its prohibition in the U.S., 5-MeO-DiPT was sold online alongside psychoactive analogues such as
DiPT
Diisopropyltryptamine (; also known as ''N,N''-diisopropyltryptamine or DiPT) is a psychedelic hallucinogenic drug of the tryptamine family that has a unique effect. While the majority of hallucinogens affect the visual sense, DiPT is primarily ...
, and
DPT DPT may refer to:
Science and medicine
* Dpt (unit) (dioptre/diopter), most commonly a unit measuring refraction and power in a lens or curved mirror
*Dermatopontin, a human extracellular matrix protein
* Dipropyltryptamine, a psychedelic tryptami ...
, neither of which have yet been expressly outlawed.
See also
*
5-MeO-DiBF
*
5-MeO-DMT
5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine) or O-methyl-bufotenin is a psychedelic of the tryptamine class. It is found in a wide variety of plant species, and also is secreted by the glands of at least one toad species, the Colorado R ...
*
5-MeO-DPT
*
5-MeO-AMT
*
5-MeO-MiPT
5-MeO-MiPT is a psychedelic and hallucinogenic drug, used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs 5-MeO-DiPT, DiPT, and MiPT. It is commonly used as a "substitute" for 5-MeO-DiPT because ...
*
DMT
*
DPT DPT may refer to:
Science and medicine
* Dpt (unit) (dioptre/diopter), most commonly a unit measuring refraction and power in a lens or curved mirror
*Dermatopontin, a human extracellular matrix protein
* Dipropyltryptamine, a psychedelic tryptami ...
*
AMT
*
DIPT
Diisopropyltryptamine (; also known as ''N,N''-diisopropyltryptamine or DiPT) is a psychedelic hallucinogenic drug of the tryptamine family that has a unique effect. While the majority of hallucinogens affect the visual sense, DiPT is primarily ...
*
MIPT
''N''-Methyl-''N''-isopropyltryptamine (MiPT) is a psychedelic tryptamine, closely related to DMT, DiPT and Miprocin.
Chemistry
MiPT base, unlike many other tryptamines in their freebase form, does not decompose rapidly in the presence of lig ...
References
External links
Official Ruling Placing 5-MeO-DIPT into Schedule IErowid information on 5-MeO-DIPT
5-MeO-DIPT entry in TiHKAL • info
{{DEFAULTSORT:Methoxy-N N-diisopropyltryptamine 5-
Designer drugs
Phenol ethers
Psychedelic tryptamines
Serotonin receptor agonists
Neurotoxins
Diisopropylamino compounds