3,5-Dihydroxybenzoic acid (α-resorcylic acid) is a
dihydroxybenzoic acid Dihydroxybenzoic acids (DHBA) are a type of phenolic acids.
There are six main compounds, having all the same molecular formula C7H6O4. Those are:
* 2,3-Dihydroxybenzoic acid (2-Pyrocatechuic acid or hypogallic acid)
* 2,4-Dihydroxybenzoic acid ...
. It is a colorless solid.
Preparation and occurrence
It is prepared by di
sulfonation Aromatic sulfonation is an organic reaction in which a hydrogen atom on an arene is replaced by a sulfonic acid functional group in an electrophilic aromatic substitution. Aryl sulfonic acids are used as detergents, dye, and drugs.
Stoichiometry a ...
of
benzoic acid
Benzoic acid is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin ...
followed by hydrolysis of the disulfonate.
It is a
metabolite
In biochemistry, a metabolite is an intermediate or end product of metabolism.
The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, ...
of
alkylresorcinols, first identified in human urine and can be quantified in urine and plasma, and may be an alternative, equivalent
biomarker
In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, p ...
of whole grain wheat intake.
References
Dihydroxybenzoic acids
Phenolic human metabolites
{{phenol-stub