3',5'-cyclic-AMP phosphodiesterase
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3′,5′-cyclic-AMP phosphodiesterase (EC 3.1.4.53, cAMP-specific phosphodiesterase, cAMP-specific PDE,
PDE1 Phosphodiesterase 1, PDE1, EC 3.1.4.1, systematic name oligonucleotide 5′-nucleotidohydrolase) is a phosphodiesterase enzyme also known as calcium- and calmodulin-dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PD ...
, PDE2A, PDE2B, PDE4, PDE7, PDE8, PDEB1, PDEB2) is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...
3′,5′-cyclic-AMP 5′-nucleotidohydrolase. It catalyses the following reaction : adenosine 3′,5′-cyclic phosphate + H2O \rightleftharpoons AMP This enzyme requires Mg2+ or Mn2+ for activity.


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* {{Portal bar, Biology, border=no EC 3.1.4