2009 Gujarat hepatitis outbreak
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The 2009 Gujarat hepatitis B outbreak was a cluster of
hepatitis B Hepatitis B is an infectious disease caused by the '' Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. ...
cases that appeared in
Modasa Modasa is a town and a municipality in Aravalli district in the Indian state of Gujarat. Modasa was named after the Bhil chieftain Malaji Bhil, who ruled in Modasa during 1466. Modasa became headquarters of new Aravalli district, carved out ...
, northern
Gujarat Gujarat (, ) is a state along the western coast of India. Its coastline of about is the longest in the country, most of which lies on the Kathiawar peninsula. Gujarat is the fifth-largest Indian state by area, covering some ; and the ninth ...
,
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
in 2009. Over 125 people were infected and up to 49 people died. Several doctors were investigated and arrested after the outbreaks.


Hepatitis B

The hepatitis B virus infects the
liver The liver is a major organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it ...
and causes an
inflammation Inflammation (from la, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molec ...
called
hepatitis Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes ( jaundice), poor appetite, vomiting, tiredness, abdominal ...
. It is a
DNA virus A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and ...
and one of many unrelated viruses that cause
viral hepatitis Viral hepatitis is liver inflammation due to a viral infection. It may present in acute form as a recent infection with relatively rapid onset, or in chronic form. The most common causes of viral hepatitis are the five unrelated hepatotropic vi ...
. The disease, originally known as "serum hepatitis", has caused
epidemic An epidemic (from Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of patients among a given population within an area in a short period of time. Epidemics of infectious ...
s in parts of
Asia Asia (, ) is one of the world's most notable geographical regions, which is either considered a continent in its own right or a subcontinent of Eurasia, which shares the continental landmass of Afro-Eurasia with Africa. Asia covers an are ...
and
Africa Africa is the world's second-largest and second-most populous continent, after Asia in both cases. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 6% of Earth's total surface area ...
, and it is
endemic Endemism is the state of a species being found in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found else ...
in China. About a third of the world's population, more than 2 billion people, have been infected with the hepatitis B virus. This includes 350 million chronic carriers of the virus. The acute illness causes liver inflammation, vomiting and jaundice. The infection is preventable by
vaccination Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating ...
. Transmission of hepatitis B results from exposure to infectious blood or body fluids containing blood. Possible forms of transmission include (but are not limited to) unprotected sexual contact,
blood transfusion Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but mo ...
s, re-use of contaminated needles & syringes, and vertical transmission from mother to child during childbirth. HBV can be transmitted between family members within households, possibly by contact of nonintact skin or mucous membrane with secretions or saliva containing HBV. However, at least 30% of reported cases of hepatitis B among adults cannot be associated with an identifiable risk factor.


Arrests

The doctors were accused of re-using syringes, which had been contaminated with
hepatitis B virus ''Hepatitis B virus'' (HBV) is a partially double-stranded DNA virus, a species of the genus '' Orthohepadnavirus'' and a member of the '' Hepadnaviridae'' family of viruses. This virus causes the disease hepatitis B. Disease Despite there b ...
, to treat other patients. Eight medical practitioners, including doctors Govind and Chintal Patel, were arrested under the
Indian Penal Code The Indian Penal Code (IPC) is the official criminal code of India. It is a comprehensive code intended to cover all substantive aspects of criminal law. The code was drafted on the recommendations of first law commission of India established ...
for culpable homicide not amounting to murder after allegedly re-using infected syringes. One of them was also charged with attempted murder. Most of the people affected had received medical treatment from Dr. Patel in the last six months. Medical officials conducted a raid on Patel's clinic and found several used syringes and other medical waste.


Reaction

The
Government of Gujarat The Government of Gujarat, also known as Gujarat Government, is the supreme governing authority of the Indian state of Gujarat and its 33 districts. It consists of an executive of the legislators appointed by the Governor of Gujarat, a judiciar ...
started a mass
immunization Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an infectious agent (known as the immunogen). When this system is exposed to molecules that are foreign to the body, called ''non-se ...
drive under strict medical supervision in Modasa, which set up 60 booths in Modasa and nearby cities. 224 medical teams, including some from All Indian Institute of Medical Sciences and
National Institute of Virology The National Institute of Virology in Pune, India is an Indian virology research institute and part of the Indian Council of Medical Research (ICMR). It was previously known as 'Virus Research Centre' and was founded in collaboration with the ...
set up camps in Modasa and remained there for about a month. According to the officials 25,000
vaccines A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified.< ...
were sent to the most affected area and 600,000 more vaccines was arranged from
Hyderabad Hyderabad ( ; , ) is the capital and largest city of the Indian state of Telangana and the ''de jure'' capital of Andhra Pradesh. It occupies on the Deccan Plateau along the banks of the Musi River, in the northern part of Southern India ...
. In addition, the government distributed 30,000 pamphlets and mounted a campaign to inform residents about the disease. The Health Department of the Gujarat government have sent 600,000 doses of vaccine to the area.


See also

* Introduction to viruses *
Virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsk ...


References

{{Epidemics Hepatitis outbreaks Gujarat hepatitis outbreak Gujarat hepatitis outbreak Disease outbreaks in India 21st-century epidemics History of Gujarat (1947–present) Disasters in Gujarat Hepatitis B Healthcare in Gujarat