20α-Dihydrodydrogesterone (20α-DHD), also known as 20α-hydroxydydrogesterone, as well as 20(''S'')-hydroxy-9β,10α-pregna-4,6-dien-3-one, is a progestin and the major active metabolite of dydrogesterone.
It appears that dydrogesterone is a prodrug of 20α-DHD, as it is largely biotransformation, transformed into this metabolite when given oral administration, orally in humans.
20α-DHD has progestogenic activity similarly to dydrogesterone, but is far less potency (pharmacology), potent in comparison.
See also
* 20α-Dihydroprogesterone
* 20α-Dihydrotrengestone
References
Secondary alcohols
Conjugated dienes
Human drug metabolites
Enones
Pregnanes
Progestogens
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