1-Methylamino-1-(3,4-methylenedioxyphenyl)propane
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1-Methylamino-1-(3,4-methylenedioxyphenyl)propane or M-ALPHA is an empathogen, reported by
Alexander Shulgin Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing 3,4-methylenedioxymethamph ...
in his book PIHKAL as a positional isomer of MDMA, and subsequently found being sold as a designer drug in the UK in 2010, and reported to the EMCDDA new drug monitoring service.EMCDDA Annual Report 2010
/ref> It was described by Alexander Shulgin as similar in action to its demethylated homologue,
ALPHA Alpha (uppercase , lowercase ; grc, ἄλφα, ''álpha'', or ell, άλφα, álfa) is the first letter of the Greek alphabet. In the system of Greek numerals, it has a value of one. Alpha is derived from the Phoenician letter aleph , whic ...
, but with roughly twice the duration and twice the potency.


See also

*
Filenadol Filenadol (INN; Filantor; FI-2024) is an analgesic drug with antinociceptive Nociception (also nocioception, from Latin ''nocere'' 'to harm or hurt') is the Somatosensory system, sensory nervous system's process of encoding Noxious stimulus, nox ...
*
Isoethcathinone Isoethcathinone is a designer drug with purportedly stimulant effects, first encountered in Ireland in 2010 and reported to the EMCDDA new drug monitoring service. It is unclear whether it has desirable pharmacological properties in its own right ...

MDA entry in PiHKAL
* Methylenedioxyphencyclidine *
M-alpha-HMCA M-alpha-HMCA (''3-(benzo 1,3]dioxol-5-yl)-2-hydroxy-N,2-dimethyl-3-(methylamino)propanamide'') is an unintentional sideproduct during the synthesis of MDMA using PMK glycidate as a precursor. It was identified in MDMA pills. The biological pro ...


References

Designer drugs Psychedelic drugs {{nervous-system-drug-stub