Øjvind Winge
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Øjvind Winge (May 19, 1886 – April 5, 1964) was a
Danish Danish may refer to: * Something of, from, or related to the country of Denmark People * A national or citizen of Denmark, also called a "Dane," see Demographics of Denmark * Culture of Denmark * Danish people or Danes, people with a Danish a ...
biologist A biologist is a scientist who conducts research in biology. Biologists are interested in studying life on Earth, whether it is an individual Cell (biology), cell, a multicellular organism, or a Community (ecology), community of Biological inter ...
and a pioneer in
yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constit ...
genetics.


Education

Winge was born in the city of Aarhus in
Jutland Jutland ( da, Jylland ; german: Jütland ; ang, Ēota land ), known anciently as the Cimbric or Cimbrian Peninsula ( la, Cimbricus Chersonesus; da, den Kimbriske Halvø, links=no or ; german: Kimbrische Halbinsel, links=no), is a peninsula of ...
, the mainland of Denmark. After completing secondary school he travelled to the
University of Copenhagen The University of Copenhagen ( da, Københavns Universitet, KU) is a prestigious public research university in Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia after Uppsala Unive ...
to study law but found himself more suited to the
biological science Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary ...
s into which he transferred. He graduated with a master's degree in the year 1910. From Copenhagen he travelled to Stockholm,
Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), ma ...
and
Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
, studying mainly chromosomal
cytology Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living an ...
before finally returning to the University of Copenhagen to do a doctoral thesis entitled ''The Chromosomes: Their Numbers and General Importance''. In 1910 Winge was appointed chair of genetics at the
Royal Veterinary and Agricultural University The Royal Veterinary and Agricultural University ( da, Kongelige Veterinær- og Landbohøjskole, abbr. KVL) was a veterinary and agricultural science university in Denmark. It was founded in 1856 and operated until 2007, when it became a part of ...
, Copenhagen, where amongst other works he wrote ''The Textbook in Genetics'', published in 1928.


Career

In 1933 Winge was offered and accepted the position of Director of the Physiology Department in the
Carlsberg Laboratory The Carlsberg Research Laboratory is a private scientific research center in Copenhagen, Denmark under the Carlsberg Group. It was founded in 1875 by J. C. Jacobsen, the founder of the Carlsberg brewery, with the purpose of advancing biochemic ...
, Copenhagen. Here he dedicated his research to the 3 principal lifeforms of interest to his benefactors; hops,
barley Barley (''Hordeum vulgare''), a member of the grass family, is a major cereal grain grown in temperate climates globally. It was one of the first cultivated grains, particularly in Eurasia as early as 10,000 years ago. Globally 70% of barley p ...
and
yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constit ...
, although his studies became increasingly dedicated to yeast. He developed and used techniques to achieve the micromanipulation of single yeast cells and spores in order to investigate them on a genetic level. He found that yeast spores are haploid, and diploid cells occur as a result of conjugation of two haploid cells or self-diploidisation. This was important as it revealed that the species exhibits alternation and that strains can be genetically manipulated by specific mating. Winge also demonstrated that the traits of the organisms were mainly governed by simple Mendelian rules. He continued his research and his lab produced a steady output of genetics papers until 1961. Winge's work was of critical importance to the basic formation of early genetic engineering and
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used ...
. He helped to establish a firm basis for what have now developed into important and lucrative scientific fields. For this reason he is often attributed the title of 'The Father of Yeast Genetics'.


Winge's 1917 hypothesis

In his 1917 doctoral thesis ''The Chromosomes: Their Numbers and General Importance'', Winge presented his hypothesis of plant hybridization, which has motivated much research.


Awards and honours

Winge was elected foreign member of the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
in 1947.


Selected bibliography

* Ferdinandsen, C. & Winge, Ø. (1910) Fungi from Professor Warming's expedition to
Venezuela Venezuela (; ), officially the Bolivarian Republic of Venezuela ( es, link=no, República Bolivariana de Venezuela), is a country on the northern coast of South America, consisting of a continental landmass and many islands and islets in th ...
and the
West Indies The West Indies is a subregion of North America, surrounded by the North Atlantic Ocean and the Caribbean Sea that includes 13 independent island countries and 18 dependencies and other territories in three major archipelagos: the Greate ...
.
Botanisk Tidsskrift ''Botanisk Tidsskrift'' (standard abbreviation ''Bot. Tidsskr.'') was a Danish mixed scientific and amateur journal concerning botany, issued in Copenhagen by the Danish Botanical Society. It was published from 1866 to 1980, when it fused with Bot ...
, 30, 211-. * Ferdinandsen, C. & Winge, Ø. (1914) Ostenfeldiella - a new genus of
Plasmodiophoraceae The plasmodiophores (also known as plasmophorids or plasmodiophorids) are a group of obligate endoparasitic protists belonging to the subphylum Endomyxa in Cercozoa. Taxonomically, they are united under a single family Plasmodiophoridae, order Pl ...
. ''Annals of Botany'', 28, 643-649. Named for Carl Hansen Ostenfeld. * Winge Ø. (1914) Investigations on hops ( Humulus lupulus, L.). III. The pollination and fertilization process in Humulus lupulus L. and H. japonicus Sieb. et. Zucc. Comptes Rendus des Travaux du Laboratoire Carlsberg, 11, 1-46. * Winge, Ø. (1917) The chromosomes: their numbers and general importance. Comptes Rendus des Travaux du Laboratoire Carlsberg, 13, 131-275.
Doctoral thesis A thesis ( : theses), or dissertation (abbreviated diss.), is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings.International Standard ISO 7144: ...
. * Winge, Ø. (1928) Textbook in Genetics (Danish title: ). 2nd edn. 1937; 3rd end. 1945.
København Copenhagen ( or .; da, København ) is the capital and most populous city of Denmark, with a proper population of around 815.000 in the last quarter of 2022; and some 1.370,000 in the urban area; and the wider Copenhagen metropolitan ar ...
. * Winge Ø. (1931) X- and Y-linked inheritance in Melandrium. Hereditas, 15, 127-165. * Winge, Ø. (1935) On haplophase and diplophase of some
Saccharomycetes Saccharomycetes belongs to the Ascomycota division of the kingdom Fungi. It is the only class in the subdivision Saccharomycotina, the budding yeasts. Saccharomycetes contains a single order, Saccharomycetales Saccharomycetales belongs to the ...
. Comptes Rendus des Travaux du Laboratoire Carlsberg. Série Physiologique, 21, 77-111. * Winge, Ø. (1950) Inheritance in dogs: with special reference to hunting breeds. Ithaca, New York. 153 p.


References

{{DEFAULTSORT:Winge, Ojvind 1886 births 1964 deaths Danish biologists Danish mycologists Danish geneticists University of Copenhagen alumni Carlsberg Laboratory staff Foreign Members of the Royal Society Foreign associates of the National Academy of Sciences 20th-century biologists