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Stearoylethanolamide
Stearoylethanolamide (SEA) is an endocannabinoid neurotransmitter. Stearoylethanolamide ( C20 H41 NO2; 18:0), also called N-(octadecanoyl)ethanolamine, is an N-acylethanolamine and the ethanolamide of octadecanoic acid Stearic acid ( , ) is a saturated fatty acid with an 18-carbon chain. The IUPAC name is octadecanoic acid. It is a waxy solid and its chemical formula is C17H35CO2H. Its name comes from the Greek word στέαρ "''stéar''", which means tallow. ... (C18H36 O2; 18:0) and ethanolamine (MEA: C2H7NO), and functionally related to an octadecanoic acid. Levels of SEA correlate with changes in pain intensity, indicating this SEA change, reflect the pain reduction effects of IPRP. References Endocannabinoids Neurotransmitters Fatty acid amides {{biochemistry-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Acylethanolamine
An ''N''-acylethanolamine (NAE) is a type of fatty acid amide where one of several types of acyl groups is linked to the nitrogen atom of ethanolamine, and highly metabolic formed by intake of essential fatty acids through diet by 20:4, n-6 and 22:6, n-3 fatty acids, and when the body is physically and psychologically active, and the endocannabinoid signaling system (ECS) is the major pathway by which NAEs exerts its physiological effects in animal cells with similarities in plants, and the metabolism of NAEs is an integral part of the ECS. These amides conceptually can be formed from a fatty acid and ethanolamine with the release of a molecule of water, but the known biological synthesis uses a specific phospholipase D to cleave the phospholipid unit from ''N''-acylphosphatidylethanolamines. Another route relies on the transesterification of acyl groups from phosphatidylcholine by an ''N''-acyltransferase (NAT) activity. The suffixes ''-amine'' and ''-amide'' in these na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
