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Mesothelium
The mesothelium is a membrane composed of simple squamous epithelial cells of mesodermal origin, which forms the lining of several body cavities: the pleura ( pleural cavity around the lungs), peritoneum ( abdominopelvic cavity including the mesentery, omenta, falciform ligament and the perimetrium) and pericardium (around the heart). Mesothelial tissue also surrounds the male testis (as the tunica vaginalis) and occasionally the spermatic cord (in a patent processus vaginalis). Mesothelium that covers the internal organs is called visceral mesothelium, while one that covers the surrounding body walls is called the parietal mesothelium. The mesothelium that secretes serous fluid as a main function is also known as a serosa. Origin Mesothelium derives from the embryonic mesoderm cell layer, that lines the coelom (body cavity) in the embryo. It develops into the layer of cells that covers and protects most of the internal organs of the body. Structure The mesotheli ...
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Epithelial Cell
Epithelium or epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. It is a thin, continuous, protective layer of compactly packed cells with a little intercellular matrix. Epithelial tissues line the outer surfaces of organs and blood vessels throughout the body, as well as the inner surfaces of cavities in many internal organs. An example is the epidermis, the outermost layer of the skin. There are three principal shapes of epithelial cell: squamous (scaly), columnar, and cuboidal. These can be arranged in a singular layer of cells as simple epithelium, either squamous, columnar, or cuboidal, or in layers of two or more cells deep as stratified (layered), or ''compound'', either squamous, columnar or cuboidal. In some tissues, a layer of columnar cells may appear to be stratified due to the placement of the nuclei. This sort of tissue is called pseudostratified. All glands are made up of epith ...
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Pericardium
The pericardium, also called pericardial sac, is a double-walled sac containing the heart and the roots of the great vessels. It has two layers, an outer layer made of strong connective tissue (fibrous pericardium), and an inner layer made of serous membrane (serous pericardium). It encloses the pericardial cavity, which contains pericardial fluid, and defines the middle mediastinum. It separates the heart from interference of other structures, protects it against infection and blunt trauma, and lubricates the heart's movements. The English name originates from the Ancient Greek prefix "''peri-''" (περί; "around") and the suffix "''-cardion''" (κάρδιον; "heart"). Anatomy The pericardium is a tough fibroelastic sac which covers the heart from all sides except at the cardiac root (where the great vessels join the heart) and the bottom (where only the serous pericardium exists to cover the upper surface of the central tendon of diaphragm). The fibrous perica ...
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Peritoneum
The peritoneum is the serous membrane forming the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids. It covers most of the intra-abdominal (or coelomic) organs, and is composed of a layer of mesothelium supported by a thin layer of connective tissue. This peritoneal lining of the cavity supports many of the abdominal organs and serves as a conduit for their blood vessels, lymphatic vessels, and nerves. The abdominal cavity (the space bounded by the vertebrae, abdominal muscles, diaphragm, and pelvic floor) is different from the intraperitoneal space (located within the abdominal cavity but wrapped in peritoneum). The structures within the intraperitoneal space are called "intraperitoneal" (e.g., the stomach and intestines), the structures in the abdominal cavity that are located behind the intraperitoneal space are called " retroperitoneal" (e.g., the kidneys), and those structures below the intraperitoneal space are calle ...
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Pleura
The pulmonary pleurae (''sing.'' pleura) are the two opposing layers of serous membrane overlying the lungs and the inside of the surrounding chest walls. The inner pleura, called the visceral pleura, covers the surface of each lung and dips between the lobes of the lung as ''fissures'', and is formed by the invagination of lung buds into each thoracic sac during embryonic development. The outer layer, called the parietal pleura, lines the inner surfaces of the thoracic cavity on each side of the mediastinum, and can be subdivided into ''mediastinal'' (covering the side surfaces of the fibrous pericardium, oesophagus and thoracic aorta), ''diaphragmatic'' (covering the upper surface of the diaphragm), ''costal'' (covering the inside of rib cage) and cervical (covering the underside of the suprapleural membrane) pleurae. The visceral and the mediastinal parietal pleurae are connected at the root of the lung ("hilum") through a smooth fold known as ''pleural reflecti ...
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Serosa
The serous membrane (or serosa) is a smooth tissue membrane of mesothelium lining the contents and inner walls of body cavities, which secrete serous fluid to allow lubricated sliding movements between opposing surfaces. The serous membrane that covers internal organs is called a ''visceral'' membrane; while the one that covers the cavity wall is called the ''parietal'' membrane. Between the two opposing serosal surfaces is often a potential space, mostly empty except for the small amount of serous fluid. The Latin anatomical name is '' tunica serosa''. Serous membranes line and enclose several body cavities, also known as serous cavities, where they secrete a lubricating fluid which reduces friction from movements. Serosa is entirely different from the adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. The serous membrane covering the heart and lining the mediastinum is referred to as the pericardium, the se ...
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Somatopleuric Mesenchyme
In the anatomy of an embryo, the somatopleure is a structure created during embryogenesis when the lateral plate mesoderm splits into two layers. The outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it (partially) forms the somatopleure. The combination of ectoderm and mesoderm, or somatopleure, forms the amnion, the chorion and the lateral body wall of the embryo. The limbs are formed from the somatic mesoderm cells are induced by hox genes and the expression of other molecules to suffer and epithelial-mesenchyme transition. The embryonic somatopleure is then divided into 3 sections, the anterior limb bud formation, the posterior limb bud formation and the non limb forming wall. The bud forming sections grow in size at the somatic mesoderm under the ectoderm proliferate in mesenchyme form. In chicken, the extraembryonic tissues are separated into two layers: the splanchnopleure composed of the endoderm and splanchnic mesoderm, and the ...
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Simple Squamous Epithelium
A simple squamous epithelium, also known as pavement epithelium, and tessellated epithelium is a single layer of flattened, polygonal cells in contact with the basal lamina (one of the two layers of the basement membrane) of the epithelium. This type of epithelium is often permeable and occurs where small molecules need to pass quickly through membranes via filtration or diffusion. Simple squamous epithelia are found in endothelium (lining of blood and lymph capillaries), mesothelium (coelomic epithelium/peritoneum), alveoli of lungs, glomeruli ''Glomerulus'' () is a common term used in anatomy to describe globular structures of entwined vessels, fibers, or neurons. ''Glomerulus'' is the diminutive of the Latin ''glomus'', meaning "ball of yarn". ''Glomerulus'' may refer to: * the filt ..., and other tissues where rapid diffusion is required.AAMC - 2015 MCAT Question Pack Explanations Within the cardiovascular system such as lining capillaries or the inside of the heart, si ...
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Mesoderm
The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.Langman's Medical Embryology, 11th edition. 2010. The mesoderm forms mesenchyme, mesothelium, non-epithelial blood cells and coelomocytes. Mesothelium lines coeloms. Mesoderm forms the muscles in a process known as myogenesis, septa (cross-wise partitions) and mesenteries (length-wise partitions); and forms part of the gonads (the rest being the gametes). Myogenesis is specifically a function of mesenchyme. The mesoderm differentiates from the rest of the embryo through intercellular signaling, after which the mesoderm is polarized by an organizing center. The position of the organizing center is in turn determined by the regions in which beta-catenin is protected from degradation by GSK-3. Beta-catenin acts as a co-factor that alters the activity of ...
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Body Cavities
A body cavity is any space or compartment, or potential space, in an animal body. Cavities accommodate organs and other structures; cavities as potential spaces contain fluid. The two largest human body cavities are the ventral body cavity, and the dorsal body cavity. In the dorsal body cavity the brain and spinal cord are located. The membranes that surround the central nervous system organs (the brain and the spinal cord, in the cranial and spinal cavities) are the three meninges. The differently lined spaces contain different types of fluid. In the meninges for example the fluid is cerebrospinal fluid; in the abdominal cavity the fluid contained in the peritoneum is a serous fluid. In amniotes and some invertebrates the peritoneum lines their largest body cavity called the coelom. Mammals Mammalian embryos develop two body cavities: the intraembryonic coelom and the extraembryonic coelom (or chorionic cavity). The intraembryonic coelom is lined by somatic and splanchnic ...
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Mesentery
The mesentery is an organ that attaches the intestines to the posterior abdominal wall in humans and is formed by the double fold of peritoneum. It helps in storing fat and allowing blood vessels, lymphatics, and nerves to supply the intestines, among other functions. The mesocolon was thought to be a fragmented structure, with all named parts—the ascending, transverse, descending, and sigmoid mesocolons, the mesoappendix, and the mesorectum—separately terminating their insertion into the posterior abdominal wall. However, in 2012, new microscopic and electron microscopic examinations showed the mesocolon to be a single structure derived from the duodenojejunal flexure and extending to the distal mesorectal layer. Thus, the mesentery is an internal organ. Structure The mesentery of the small intestine arises from the root of the mesentery (or mesenteric root) and is the part connected with the structures in front of the vertebral column. The root is narrow, about ...
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Perimetrium
The perimetrium (or serous coat of uterus) is the outer serosal layer of the uterus, derived from the peritoneum overlying the uterine fundus, and can be considered a visceral peritoneum. It consists of a superficial layer of mesothelium, and a thin layer of loose connective tissue beneath it. Anteriorly, the perimetrium covers the fundus and upper body of the uterus until it meets the superoposterior surface of the adjacent urinary bladder, resulting in a concave fold of peritoneum called the ''vesicouterine pouch''. Posteriorly, the perimetrium covers the entire surface of the uterus deep down to the cervix, where it then folds back onto the adjacent rectum to form the ''rectouterine pouch'', the lowest gutter of the peritoneal cavity. Laterally, the perimetrium blends into the serosae of the broad ligament The broad ligament of the uterus is the wide fold of peritoneum that connects the sides of the uterus to the walls and floor of the pelvis. Structure Subdivisions Co ...
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Body Cavity
A body cavity is any space or compartment, or potential space, in an animal body. Cavities accommodate organs and other structures; cavities as potential spaces contain fluid. The two largest human body cavities are the ventral body cavity, and the dorsal body cavity. In the dorsal body cavity the brain and spinal cord are located. The membranes that surround the central nervous system organs (the brain and the spinal cord, in the cranial and spinal cavities) are the three meninges. The differently lined spaces contain different types of fluid. In the meninges for example the fluid is cerebrospinal fluid; in the abdominal cavity the fluid contained in the peritoneum is a serous fluid. In amniotes and some invertebrates the peritoneum lines their largest body cavity called the coelom. Mammals Mammalian embryos develop two body cavities: the intraembryonic coelom and the extraembryonic coelom (or chorionic cavity). The intraembryonic coelom is lined by somatic an ...
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