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Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sources It occurs naturally in several species of cacti. It is also found in small amounts in certain members of the bean family, Fabaceae, including '' Acacia berlandieri''. However those claims concerning ''Acacia'' species have been challenged and have been unsupported in any additional analysis. History and use Peyote has been used for at least 5,700 years by Indigenous peoples of the Americas in Mexico. Europeans noted use of peyote in Native American religious ceremonies upon early contact, notably by the Huichols in Mexico. Other mescaline-containing cacti such as the San Pedro have a long history of use in South America, from Peru to Ecuador. While religious and ceremonial peyote use was widespread in the Aztec empire and nor ...
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Psychoactive Cactus
Many cacti are known to be psychoactive, containing phenethylamine alkaloids such as mescaline. However, the two main ritualistic (folkloric) genera are '' Echinopsis'', of which the most psychoactive species is the San Pedro cactus (''Echinopsis pachanoi'', syn. ''Trichocereus pachanoi''), and '' Lophophora'', with peyote (''Lophophora williamsii'') being the most psychoactive species. Several other species pertaining to other genera are also psychoactive, though not always used with a ritualistic intent. Species Globular cacti *'' Lophophora williamsii'' (peyote) Other "peyotes" *'' Ariocarpus fissuratus'' *'' Coryphantha compacta'' (syn. ''C. palmeri'') *''Pelecyphora aselliformis'' *''Pelecyphora strobiliformis'' *''Lophophora diffusa'' *''Ariocarpus retusus'' *''Ariocarpus agavoides''; '' kotschoubeyanus''; and other species *'' Astrophytum asterias''; '' capricorne''; '' myriostigma''; and other species *'' Aztekium ritteri''; and other species *''Coryphantha elephanti ...
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Psychedelic Drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence'' Sometimes, they are called classic hallucinogens, serotonergic hallucinogens, or serotonergic psychedelics, and the term ''psychedelics'' is used more broadly to include all hallucinogens; this article uses the narrower definition of ''psychedelics''. Psychedelics cause specific psychological, visual, and auditory changes, and often a substantially altered state of consciousness.Leary, Timothy; Metzner, Ralph (1964). ''The Psychedelic Experience: A Manual Based on The Tibetan Book of the Dead'' Psychedelic states are often compared to meditative, psychodynamic or transcendental types of alterations of mind. The "classical" psychedelics, the ...
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Echinopsis Pachanoi
''Echinopsis pachanoi'' (syn. ''Trichocereus pachanoi'')—known as San Pedro cactus—is a fast-growing columnar cactus native to the Andes Mountains at in altitude. It is found in Argentina, Bolivia, Colombia, Chile, Ecuador and Peru, and it is cultivated in other parts of the world. Uses for it include traditional medicine and traditional veterinary medicine, and it is widely grown as an ornamental cactus. It has been used for healing and religious divination in the Andes Mountains region for over 3,000 years. It is sometimes confused with its close relative '' Echinopsis peruviana'' (Peruvian torch cactus). Taxonomy Echinopsis pachanoi is known by many names throughout South America such as ''achuma,'' ''huachuma,'' ''wachuma,'' ''aguacolla,'' ''hahuacollay,'' ''San Pedro'' or ''giganton''. Description ''Echinopsis pachanoi'' is native to Ecuador and Peru. Its stems are light to dark green, sometimes glaucous, with a diameter of and usually 6–8 ribs. The whitish areoles ...
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Peyote
The peyote (; ''Lophophora williamsii'' ) is a small, spineless cactus which contains Psychoactive cactus, psychoactive alkaloids, particularly mescaline. ''Peyote'' is a Spanish word derived from the Nahuatl (), meaning "caterpillar Pupa#Cocoon, cocoon", from a root , "to glisten". p. 246. See wikt:peyotl, peyotl in Wiktionary. Peyote is native to Mexico and southwestern Texas. It is found primarily in the Sierra Madre Occidental, the Chihuahuan Desert and in the States of Mexico, states of Nayarit, Coahuila, Nuevo León, Tamaulipas, and San Luis Potosí among scrub. It flowers from March to May, and sometimes as late as September. The flowers are pink, with thigmotactic anthers (like ''Opuntia''). Known for its psychoactive properties when ingested, peyote has at least 5,500 years of entheogenic and traditional medicine, medicinal use by Indigenous people of the Americas, indigenous North Americans. Description The various species of the genus ''Lophophora'' grow low to th ...
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Peyote
The peyote (; ''Lophophora williamsii'' ) is a small, spineless cactus which contains Psychoactive cactus, psychoactive alkaloids, particularly mescaline. ''Peyote'' is a Spanish word derived from the Nahuatl (), meaning "caterpillar Pupa#Cocoon, cocoon", from a root , "to glisten". p. 246. See wikt:peyotl, peyotl in Wiktionary. Peyote is native to Mexico and southwestern Texas. It is found primarily in the Sierra Madre Occidental, the Chihuahuan Desert and in the States of Mexico, states of Nayarit, Coahuila, Nuevo León, Tamaulipas, and San Luis Potosí among scrub. It flowers from March to May, and sometimes as late as September. The flowers are pink, with thigmotactic anthers (like ''Opuntia''). Known for its psychoactive properties when ingested, peyote has at least 5,500 years of entheogenic and traditional medicine, medicinal use by Indigenous people of the Americas, indigenous North Americans. Description The various species of the genus ''Lophophora'' grow low to th ...
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Echinopsis Peruviana
''Echinopsis peruviana'' (syn. ''Trichocereus peruvianus''), the Peruvian torch cactus, is a fast-growing columnar cactus native to the western slope of the Andes in Peru, between about above sea level. Description The plant is bluish-green in color, with frosted stems, and 6-9 broadly rounded ribs; it has large, white flowers. It can grow up to tall, with stems up to in diameter; it is fully erect to begin with, but later possibly arching over, or even becoming prostrate. Groups of 6-8 honey-colored to brown rigid spines, up to in length, with most about , are located at the nodes, which are evenly spaced along the ribs, up to approximately apart. Taxonomy Subspecies ''Echinopsis peruviana'' ssp. ''puquiensis'' ( Rauh & Backeb.) Ostolaza Varieties Some varieties, with scientifically invalid names, of ''Echinopsis peruviana'' are: * var. ''ancash'' (KK1688), San Marcos, Ancash, northwest Peru. * var. ''ayacuchensis'' (KK2151), southwestern Peru. * var. ''cuzcoensis'' ( ...
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Substituted Phenethylamine
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents. The structural formula of any substituted phenethylamine contains a phenyl ring that is joined to an amino (NH) group via a two-carbon sidechain. Hence, any substituted phenethylamine can be classified according to the substitution of hydrogen (H) atoms on phenethylamine's phenyl ring, sidechain, or amino group with a specific group of atoms. Many substituted phenethylamines are psychoactive drugs which belong to a variety of different drug classes, including central nervous system stimulants (e.g., amphetamine), hallucinogens (e.g., dl-2,5-dimethoxy-4-methylamphetamine DOM), entactogens (e.g., 3,4-methylenedioxyamphe ...
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Ernst Späth
Ernst Späth (; 14 May 1886 in Moravský Beroun – 30 September 1946 in Zurich) was an Austrian chemist, specializing in natural products. Life Späth was the first to synthesise mescaline and was one of the first to synthesize cuscohygrine on a small scale with Hans Tuppy. He lost everything in World War II, and died with no money. His former student Percy Lavon Julian returned to Vienna, paid for his funeral, and commissioned a bust of Späth, which is still displayed in the foyer of the ''Faculty of Chemistry'' of the University of Vienna The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich hi .... A second cast of the bust was erected in 1961 in the ''Arkadenhof'' of the University of Vienna. References Biography * Publications * Austrian chemists 1886 births 1946 de ...
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Christopher Mayhew
Christopher Paget Mayhew, Baron Mayhew (12 June 1915 – 7 January 1997) was a British politician who was a Labour Member of Parliament (MP) from 1945 to 1950 and from 1951 to 1974, when he left the Labour Party to join the Liberals. In 1981 Mayhew received a life peerage and was raised to the House of Lords as Baron Mayhew. He is most known for his central role in founding the Information Research Department (IRD), a secret wing of the UK Foreign Office dedicated to Cold War propaganda. Early life Christopher Paget Mayhew was the son of Sir Basil Mayhew of Felthorpe Hall, Norwich. Mayhew attended Haileybury and Christ Church, Oxford, as an exhibitioner. In 1934 he holidayed in Moscow. While he was at Oxford, he became President of the Oxford Union. He was commissioned into the Intelligence Corps in 1940, rising to the rank of Major. Political career Mayhew was elected to Parliament for the constituency of South Norfolk in the general election of 1945. In 1945, Mayhew ...
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Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including bacteria, fungi,
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Hallucinogen
Hallucinogens are a large, diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorized as either being psychedelics, dissociatives, or deliriants. However, certain hallucinogens such as Fly agaric as well as other gabaergic hallucinogenics are more often considered to technically be hypnotics, therefore indicating another separate subcategory of drugs which can substantially alter visual perception. Etymology The word ''hallucinogen'' is derived from the word ''hallucination''. The term ''hallucinate'' dates back to around 1595–1605, and is derived from the Latin ''hallūcinātus'', the past participle of ''(h)allūcināri'', meaning "to wander in the mind." Characteristics Leo Hollister gave five criteria for classifying a drug as hallucinogenic.Glennon RA. Classical drugs: an introductory overview. In Lin GC and ...
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Convention On Psychotropic Substances
The Convention on Psychotropic Substances of 1971 is a United Nations treaty designed to control psychoactive drugs such as amphetamine-type stimulants, barbiturates, benzodiazepines, and psychedelics signed in Vienna, Austria on 21 February 1971. The Single Convention on Narcotic Drugs of 1961 did not ban the many newly discovered psychotropics, since its scope was limited to drugs with cannabis, coca and opium-like effects. During the 1960s such drugs became widely available, and government authorities opposed this for numerous reasons, arguing that along with negative health effects, drug use led to lowered moral standards. The Convention, which contains import and export restrictions and other rules aimed at limiting drug use to scientific and medical purposes, came into force on 16 August 1976. As of 2013, 183 member states are Parties to the treaty. Many laws have been passed to implement the Convention, including the Canadian Controlled Drugs and Substances Act, th ...
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