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Mauveine
Mauveine, also known as aniline purple and Perkin's mauve, was one of the first synthetic dyes. It was discovered serendipitously by William Henry Perkin in 1856 while he was attempting to synthesise the phytochemical quinine for the treatment of malaria. It is also among the first chemical dyes to have been mass-produced. Chemistry Mauveine is a mixture of four related aromatic compounds differing in number and placement of methyl groups. Its organic synthesis involves dissolving aniline, ''p''-toluidine, and ''o''-toluidine in sulfuric acid and water in a roughly 1:1:2 ratio, then adding potassium dichromate. Mauveine A () incorporates 2 molecules of aniline, one of ''p''-toluidine, and one of ''o''-toluidine. Mauveine B () incorporates one molecule each of aniline, ''p''-toluidine, and two of ''o''-toluidine. In 1879, Perkin showed mauveine B related to safranines by oxidative/ reductive loss of the ''p''-tolyl group. In fact, safranine is a 2,8-dimethyl phenaziniu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Henry Perkin
Sir William Henry Perkin (12 March 1838 – 14 July 1907) was a British chemist and entrepreneur best known for his serendipitous discovery of the first commercial synthetic organic dye, mauveine, made from aniline. Though he failed in trying to synthesise quinine for the treatment of malaria, he became successful in the field of dyes after his first discovery at the age of 18. Perkin set up a factory to produce the dye industrially. Lee Blaszczyk, professor of business history at the University of Leeds, states, "By laying the foundation for the synthetic organic chemicals industry, Perkin helped to revolutionize the world of fashion." Early years William Perkin was born in the East End of London, the youngest of the seven children of George Perkin, a successful carpenter. His mother, Sarah, was of Scottish descent and moved to East London as a child.UXL Encyclopedia of World Biography (2003). Accessed 18 March 2008. He was baptized in the Anglican parish church of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sir William Henry Perkin
Sir William Henry Perkin (12 March 1838 – 14 July 1907) was a British chemist and entrepreneur best known for his serendipitous discovery of the first commercial synthetic organic dye, mauveine, made from aniline. Though he failed in trying to synthesise quinine for the treatment of malaria, he became successful in the field of dyes after his first discovery at the age of 18. Perkin set up a factory to produce the dye industrially. Lee Blaszczyk, professor of business history at the University of Leeds, states, "By laying the foundation for the synthetic organic chemicals industry, Perkin helped to revolutionize the world of fashion." Early years William Perkin was born in the East End of London, the youngest of the seven children of George Perkin, a successful carpenter. His mother, Sarah, was of Scottish descent and moved to East London as a child.UXL Encyclopedia of World Biography (2003). Accessed 18 March 2008. He was baptized in the Anglican parish church of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Purple
Purple is any of a variety of colors with hue between red and blue. In the RGB color model used in computer and television screens, purples are produced by mixing red and blue light. In the RYB color model historically used by painters, purples are created with a combination of red and blue pigments. In the CMYK color model used in printing, purples are made by combining magenta pigment with either cyan pigment, black pigment, or both. Purple has long been associated with royalty, originally because Tyrian purple dye, made from the mucus secretion of a species of snail, was extremely expensive in antiquity. Purple was the color worn by Roman magistrates; it became the imperial color worn by the rulers of the Byzantine Empire and the Holy Roman Empire, and later by Roman Catholic bishops. Similarly in Japan, the color is traditionally associated with the emperor and aristocracy. According to contemporary surveys in Europe and the United States, purple is the color mos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aniline
Aniline is an organic compound with the formula C6 H5 NH2. Consisting of a phenyl group attached to an amino group, aniline is the simplest aromatic amine. It is an industrially significant commodity chemical, as well as a versatile starting material for fine chemical synthesis. Its main use is in the manufacture of precursors to polyurethane, dyes, and other industrial chemicals. Like most volatile amines, it has the odor of rotten fish. It ignites readily, burning with a smoky flame characteristic of aromatic compounds. It is toxic to humans. Relative to benzene, it is electron-rich. It thus participates more rapidly in electrophilic aromatic substitution reactions. Likewise, it is also prone to oxidation: while freshly purified aniline is an almost colorless oil, exposure to air results in gradual darkening to yellow or red, due to the formation of strongly colored, oxidized impurities. Aniline can be diazotized to give a diazonium salt, which can then undergo var ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Safranine
Safranin (Safranin O or basic red 2) is a biological stain used in histology and cytology. Safranin is used as a counterstain in some staining protocols, colouring cell nuclei red. This is the classic counterstain in both Gram stains and endospore staining. It can also be used for the detection of cartilage, mucin and mast cell granules. Safranin typically has the chemical structure shown at right (sometimes described as dimethyl safranin). There is also trimethyl safranin, which has an added methyl group in the ''ortho-'' position (see Arene substitution pattern) of the lower ring. Both compounds behave essentially identically in biological staining applications, and most manufacturers of safranin do not distinguish between the two. Commercial safranin preparations often contain a blend of both types. Safranin is also used as redox indicator in analytical chemistry. Safranines Safranines are the azonium compounds of symmetrical 2,8-dimethyl-3,7-diaminophenazine. They ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
August Wilhelm Von Hofmann
August Wilhelm von Hofmann (8 April 18185 May 1892) was a German chemist who made considerable contributions to organic chemistry. His research on aniline helped lay the basis of the aniline-dye industry, and his research on coal tar laid the groundwork for his student Charles Mansfield's practical methods for extracting benzene and toluene and converting them into nitro compounds and amines. Hofmann's discoveries include formaldehyde, hydrazobenzene, the isonitriles, and allyl alcohol. He prepared three ethylamines and tetraethylammonium compounds and established their structural relationship to ammonia. After studying under Justus von Liebig at the University of Giessen, Hofmann became the first director of the Royal College of Chemistry, now part of Imperial College London, in 1845. In 1865 he returned to Germany to accept a position at the University of Berlin as a teacher and researcher. After his return he co-founded the German Chemical Society (''Deutsche Chemis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mauve
Mauve (, ; , ) is a pale purple color named after the mallow flower (French: ''mauve''). The first use of the word ''mauve'' as a color was in 1796–98 according to the ''Oxford English Dictionary'', but its use seems to have been rare before 1859. Another name for the color is mallow, with the first recorded use of ''mallow'' as a color name in English in 1611. Mauve contains more gray and more blue than a pale tint of magenta. Many pale wildflowers called "blue" are more accurately classified as mauve. Mauve is also sometimes described as pale violet. Mauveine, the first commercial aniline dye The synthetic dye mauve was first so named in 1859. Chemist William Henry Perkin, then eighteen, was attempting in 1856 to synthesize quinine, which was used to treat malaria. He noticed an unexpected residue, which turned out to be the first aniline dye. Perkin originally named the dye Tyrian purple after the historical dye, but the product was renamed ''mauve'' after it was m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to '' Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. It can be taken by mouth or intravenously. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in tonic water to impart a bitter taste. Common side effects include headache, ringing in the ears, vision issues, and sweating. More severe side effects include deafness, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy causes harm to the baby, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a naturally occurring chemical compound. How it works as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Greenford
Greenford () is a suburb in the London Borough of Ealing in west London, England, lying west from Charing Cross. It has a population of 46,787 inhabitants, or 62,126 with the inclusion of Perivale. Greenford is served by Greenford Station (London Underground Central Line and Greenford branch of the Great Western Railway mainline service). South Greenford mainline station (on the A40 Western Avenue, also on the Greenford branch of the GWR) is actually in Perivale. Neither station is in Greenford Town Centre (Greenford Broadway), which instead is served by many local buses. Nearby places include Yeading, Hanwell, Perivale, Southall, Northolt, Ealing, Sudbury and Sudbury Hill. The most prominent landmark in the suburb is Horsenden Hill, above sea level. Greenford covers a large area, including the two miles of Greenford Road, giving it three localities: North Greenford, Greenford Green, and Greenford Broadway – this is also reflected in the names of the electoral wards ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Rees (in Mauveine-dyed Bowtie)
Charles Wayne Rees CBE FRS FRSC (15 October 1927 – 21 September 2006) was a British organic chemist. Early life and education Rees was born in Egypt, and educated in England at . After three years as a laboratory technician at the Royal Aircraft Establishment he went to University College at Southampton (later the University of Southampton ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patent
A patent is a type of intellectual property that gives its owner the legal right to exclude others from making, using, or selling an invention for a limited period of time in exchange for publishing an enabling disclosure of the invention."A patent is not the grant of a right to make or use or sell. It does not, directly or indirectly, imply any such right. It grants only the right to exclude others. The supposition that a right to make is created by the patent grant is obviously inconsistent with the established distinctions between generic and specific patents, and with the well-known fact that a very considerable portion of the patents granted are in a field covered by a former relatively generic or basic patent, are tributary to such earlier patent, and cannot be practiced unless by license thereunder." – ''Herman v. Youngstown Car Mfg. Co.'', 191 F. 579, 584–85, 112 CCA 185 (6th Cir. 1911) In most countries, patent rights fall under private law and the patent holder ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skeletal Formula
The skeletal formula, or line-angle formula or shorthand formula, of an organic compound is a type of molecular structural formula that serves as a shorthand representation of a molecule's bonding and some details of its molecular geometry. A skeletal formula shows the skeletal structure or skeleton of a molecule, which is composed of the skeletal atoms that make up the molecule. It is represented in two dimensions, as on a piece of paper. It employs certain conventions to represent carbon and hydrogen atoms, which are the most common in organic chemistry. An early form of this representation was first developed by organic chemist August Kekulé, while the modern form is closely related to and influenced by the Lewis structure of molecules and their valence electrons. Hence they are sometimes termed Kekulé structures or Lewis–Kekulé structures. Skeletal formulae have become ubiquitous in organic chemistry, partly because they are relatively quick and simple to draw, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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