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Erwin Chargaff
Erwin Chargaff (11 August 1905 – 20 June 2002) was an Austro-Hungarian-born American biochemist, writer, Bucovinian Jew who emigrated to the United States during the Nazi era, and professor of biochemistry at Columbia University medical school. He wrote a well-reviewed autobiography, ''Heraclitean Fire: Sketches from a Life Before Nature''. Early life Chargaff was born on 11 August 1905 to a Jewish family in Czernowitz, Duchy of Bukovina, Austria-Hungary, which is now Chernivtsi, Ukraine. At the outbreak of World War I, his family moved to Vienna, where he attended the Maximiliansgymnasium (now the Gymnasium Wasagasse). He then went on to the Vienna College of Technology (''Technische Hochschule Wien'') where he met his future wife Vera Broido. From 1924 to 1928, Chargaff studied chemistry in Vienna, and earned a doctorate working under the direction of Fritz Feigl. He married Vera Broido in 1928. Chargaff had one son, Thomas Chargaff. From 1925 to 1930, Chargaff s ...
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Czernowitz
Chernivtsi ( uk, Чернівці́}, ; ro, Cernăuți, ; see also other names) is a city in the historical region of Bukovina, which is now divided along the borders of Romania and Ukraine, including this city, which is situated on the upper course of the Prut river in the Southwestern Ukrainian territory. Chernivtsi serves as the administrative center for the Chernivtsi raion, the Chernivtsi urban hromada, and the oblast itself. In 2021, the Chernivtsi population, by estimate, is and the latest census in 2001 was 240,600. The first document that refers to this city dates back to 1408, when Chernivtsi was a town in the region of Moldavia, formerly as a defensive fortification, and became the center of Bukovina in 1488. In 1538, Chernivtsi was under the control of the Ottoman Empire, and the Turkish control lasted for two centuries until 1774, when Austria took control of Bukovina in the aftermath of the Russo-Turkish War. Chernivtsi (known at that time as ) became ...
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Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and tissues and observe and record the effects of products in food additives and medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create grant proposals to obtain funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to cancers, and manage laboratory teams and monitor laboratory work. Biochemists also have to have th ...
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Milton Campbell
Milton Campbell (born May 15, 1976) is a former track and field athlete from the United States who mainly competes in the 400 metres. His success comes during the indoor season. At the 1999 IAAF World Indoor Championships he set a world record of 3:02.83m over 4 x 400 metres relay together with Andre Morris, Dameon Johnson and Deon Minor. Campbell won the American Indoor Championships over 400 metres in 2004 and 2006. Campbell is originally from Atlanta, Georgia. He was a junior state, regional, and national champion runner with Quicksilver Track Club from Atlanta. In junior track, Campbell was as dominant in the 1500 meters as he was in the 800 and 400 meters. Campbell was a state champion in the 400 and 800 meters for Douglass High School of northwest Atlanta in Georgia's then-largest division, 4A. Personal bests * 200 metres – 20.47 (2002)-Atlanta USA * 400 metres – 44.67 (1997)-Stuttgart Germany * 800 metres The 800 metres, or meters ( US spelling), is a co ...
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Doctor Of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a dissertation, and defend their work before a panel of other experts in the field. The completion of a PhD is often a requirement for employment as a university professor, researcher, or scientist in many fields. Individuals who have earned a Doctor of Philosophy degree may, in many jurisdictions, use the title ''Doctor'' (often abbreviated "Dr" or "Dr.") with their name, although the proper etiquette associated with this usage may also be subject to the professional ethics of their own scholarly field, culture, or society. Those who teach at universities or work in academic, educa ...
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Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a natural science that covers the elements that make up matter to the compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during a reaction with other substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both basic and applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth (botany), the formation of igneous rocks (geology), how atmospheric ozone is formed and how environmental pollutants are degraded (ecology), the properties of the soil on the moon (cosmochemistry), how medications work (pharmacology), and how to collect DNA evidence a ...
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Ukraine
Ukraine ( uk, Україна, Ukraïna, ) is a country in Eastern Europe. It is the second-largest European country after Russia, which it borders to the east and northeast. Ukraine covers approximately . Prior to the ongoing Russian invasion, it was the eighth-most populous country in Europe, with a population of around 41 million people. It is also bordered by Belarus to the north; by Poland, Slovakia, and Hungary to the west; and by Romania and Moldova to the southwest; with a coastline along the Black Sea and the Sea of Azov to the south and southeast. Kyiv is the nation's capital and largest city. Ukraine's state language is Ukrainian; Russian is also widely spoken, especially in the east and south. During the Middle Ages, Ukraine was the site of early Slavic expansion and the area later became a key centre of East Slavic culture under the state of Kievan Rus', which emerged in the 9th century. The state eventually disintegrated into rival regional powers and ...
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Chernivtsi
Chernivtsi ( uk, Чернівці́}, ; ro, Cernăuți, ; see also other names) is a city in the historical region of Bukovina, which is now divided along the borders of Romania and Ukraine, including this city, which is situated on the upper course of the Prut river in the Southwestern Ukrainian territory. Chernivtsi serves as the administrative center for the Chernivtsi raion, the Chernivtsi urban hromada, and the oblast itself. In 2021, the Chernivtsi population, by estimate, is and the latest census in 2001 was 240,600. The first document that refers to this city dates back to 1408, when Chernivtsi was a town in the region of Moldavia, formerly as a defensive fortification, and became the center of Bukovina in 1488. In 1538, Chernivtsi was under the control of the Ottoman Empire, and the Turkish control lasted for two centuries until 1774, when Austria took control of Bukovina in the aftermath of the Russo-Turkish War. Chernivtsi (known at that time as ) became ...
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Jewish
Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The people of the Kingdom of Israel and the ethnic and religious group known as the Jewish people that descended from them have been subjected to a number of forced migrations in their history" and Hebrews of historical Israel and Judah. Jewish ethnicity, nationhood, and religion are strongly interrelated, "Historically, the religious and ethnic dimensions of Jewish identity have been closely interwoven. In fact, so closely bound are they, that the traditional Jewish lexicon hardly distinguishes between the two concepts. Jewish religious practice, by definition, was observed exclusively by the Jewish people, and notions of Jewish peoplehood, nation, and community were suffused with faith in the Jewish God, the practice of Jewish (religious) l ...
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Thymine
Thymine () (symbol T or Thy) is one of the four nucleobases in the nucleic acid of DNA that are represented by the letters G–C–A–T. The others are adenine, guanine, and cytosine. Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. In RNA, thymine is replaced by the nucleobase uracil. Thymine was first isolated in 1893 by Albrecht Kossel and Albert Neumann from calf thymus glands, hence its name. Derivation As its alternate name (5-methyluracil) suggests, thymine may be derived by methylation of uracil at the 5th carbon. In RNA, thymine is replaced with uracil in most cases. In DNA, thymine (T) binds to adenine (A) via two hydrogen bonds, thereby stabilizing the nucleic acid structures. Thymine combined with deoxyribose creates the nucleoside deoxythymidine, which is synonymous with the term thymidine. Thymidine can be phosphorylated with up to three phosphoric acid groups, producing dTMP (deoxythymidine monophosphate), dTDP, or dTTP (for the di- ...
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Adenine
Adenine () (symbol A or Ade) is a nucleobase (a purine derivative). It is one of the four nucleobases in the nucleic acid of DNA that are represented by the letters G–C–A–T. The three others are guanine, cytosine and thymine. Its derivatives have a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD), flavin adenine dinucleotide (FAD) and Coenzyme A. It also has functions in protein synthesis and as a chemical component of DNA and RNA. The shape of adenine is complementary to either thymine in DNA or uracil in RNA. The adjacent image shows pure adenine, as an independent molecule. When connected into DNA, a covalent bond is formed between deoxyribose sugar and the bottom left nitrogen (thereby removing the existing hydrogen atom). The remaining structure is called an ''adenine residue'', as part of a larger molecule. Adenosine is adenine ...
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Cytosine
Cytosine () (symbol C or Cyt) is one of the four nucleobases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson-Crick base pairing, it forms three hydrogen bonds with guanine. History Cytosine was discovered and named by Albrecht Kossel and Albert Neumann in 1894 when it was hydrolyzed from calf thymus tissues. A structure was proposed in 1903, and was synthesized (and thus confirmed) in the laboratory in the same year. In 1998, cytosine was used in an early demonstration of quantum information processing when Oxford University researchers implemented the Deutsch-Jozsa algorithm on a two qubit nuclear magnetic resonance quantum computer (NMRQC). In March 2015, NASA scientists reported the formation of cytosine, along with uracil and thymi ...
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Guanine
Guanine () (symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is called guanosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. This unsaturated arrangement means the bicyclic molecule is planar. Properties Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA. Guanine has two tautomeric forms, the major keto form (see figures) and rare enol form. It binds to cytosine through three hydrogen bonds. In cytosine, the amino group acts as the hydrogen bond donor and the C-2 carbonyl and the N-3 amine as the hydrogen-bond acceptors. Guanine has the C-6 carbonyl group that acts as the hydrogen bond acceptor, while a group at N ...
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