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August Krogh
Schack August Steenberg Krogh (15 November 1874 – 13 September 1949) was a Danish professor at the department of zoophysiology at the University of Copenhagen from 1916 to 1945. He contributed a number of fundamental discoveries within several fields of physiology, and is famous for developing the Krogh Principle. In 1920 August Krogh was awarded the Nobel Prize in Physiology or Medicine for the discovery of the mechanism of regulation of the capillaries in skeletal muscle. Krogh was first to describe the adaptation of blood perfusion in muscle and other organs according to demands through opening and closing the arterioles and capillaries. Besides his contributions to medicine, Krogh was also one of the founders of what is today the Novo Nordisk company. Life He was born in Grenaa on the peninsula of Djursland in Denmark, the son of Viggo Krogh, a shipbuilder. His mother was a Romni. He was educated at the Aarhus Katedralskole in Aarhus. He attended the University of Cop ...
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Grenå
Grenaa (or Grenå) is a Danish town and seaport on the east coast of the Jutlandic peninsula. Tourism, education and commerce are important sectors in the economy of Grenaa. It is the only larger town on Djursland. Grenaa is the municipal seat, and the largest town, in Norddjurs Municipality, which covers the northern half of Djursland. History Grenaa was first mentioned in 1231. It was granted the status of a market town in 1445. Economy Grenaa has a lingering production industry just as in most of the western world. Development of tourism and educational institutions is sought to play a larger role for Grenaa in the future. The 5 km sandy Grenaa Beach is significant for tourism, with a hinterland of summer cottages, including many rentals. Grenaa is a regional shopping centre for central-eastern Djursland, an about 40 km x 40 km peninsula, protruding into the sea, between Denmark and Sweden at the entrance to the Baltic Sea. Tourism With 14.601 (2014) ...
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Capillary
A capillary is a small blood vessel from 5 to 10 micrometres (μm) in diameter. Capillaries are composed of only the tunica intima, consisting of a thin wall of simple squamous endothelial cells. They are the smallest blood vessels in the body: they convey blood between the arterioles and venules. These microvessels are the site of exchange of many substances with the interstitial fluid surrounding them. Substances which cross capillaries include water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic fluid collected in the microcirculation. During early embryonic development, new capillaries are formed through vasculogenesis, the process of blood vessel formation that occurs through a '' de novo'' production of endothelial cells that then form vascular tubes. The term ''angiogenesis'' denotes the formation of new capillaries from pre-existing blood vessels and already ...
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Frederick Banting
Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian medical scientist, physician, painter, and Nobel laureate noted as the co-discoverer of insulin and its therapeutic potential. In 1923, Banting and John Macleod received the Nobel Prize in Medicine. Banting shared the honours and award money with his colleague, Charles Best. That same year, the government of Canada granted Banting a lifetime annuity to continue his work. As to this day, Frederick Banting, who received the Nobel Prize at age 32, remains the youngest Nobel laureate for Physiology/Medicine. Early years Frederick Banting was born on November 14, 1891, in a farmhouse near Alliston, Ontario. The youngest of five children of William Thompson Banting and Margaret Grant, he attended public high school in Alliston. In 1910, he started at Victoria College, part of the University of Toronto, in the General Arts program. After failing his first year, he petitioned to join the me ...
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Insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especial ...
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Basal Metabolic Rate
Basal metabolic rate (BMR) is the rate of energy expenditure per unit time by endothermic animals at rest. It is reported in energy units per unit time ranging from watt (joule/second) to ml O2/min or joule per hour per kg body mass J/(h·kg). Proper measurement requires a strict set of criteria to be met. These criteria include being in a physically and psychologically undisturbed state and being in a thermally neutral environment while in the post- absorptive state (i.e., not actively digesting food). In bradymetabolic animals, such as fish and reptiles, the equivalent term standard metabolic rate (SMR) applies. It follows the same criteria as BMR, but requires the documentation of the temperature at which the metabolic rate was measured. This makes BMR a variant of standard metabolic rate measurement that excludes the temperature data, a practice that has led to problems in defining "standard" rates of metabolism for many mammals. Metabolism comprises the processes that th ...
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Spirometer
A spirometer is an apparatus for measuring the volume of air inspired and expired by the lungs. A spirometer measures ventilation, the movement of air into and out of the lungs. The spirogram will identify two different types of abnormal ventilation patterns, obstructive and restrictive. There are various types of spirometers that use a number of different methods for measurement (pressure transducers, ultrasonic, water gauge). Pulmonary function tests A spirometer is the main piece of equipment used for basic Pulmonary Function Tests (PFTs). Lung diseases such as asthma, bronchitis, and emphysema may be ruled out from the tests. In addition, a spirometer often is used for finding the cause of shortness of breath, assessing the effect of contaminants on lung function, the effect of medication, and evaluating progress for disease treatment. Reasons for testing * Diagnose certain types of lung disease (such as COVID-19, bronchitis, and emphysema) * Find the cause of shortness of b ...
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Homeostasis
In biology, homeostasis ( British also homoeostasis) (/hɒmɪə(ʊ)ˈsteɪsɪs/) is the state of steady internal, physical, and chemical conditions maintained by living systems. This is the condition of optimal functioning for the organism and includes many variables, such as body temperature and fluid balance, being kept within certain pre-set limits (homeostatic range). Other variables include the pH of extracellular fluid, the concentrations of sodium, potassium and calcium ions, as well as that of the blood sugar level, and these need to be regulated despite changes in the environment, diet, or level of activity. Each of these variables is controlled by one or more regulators or homeostatic mechanisms, which together maintain life. Homeostasis is brought about by a natural resistance to change when already in the optimal conditions, and equilibrium is maintained by many regulatory mechanisms: it is thought to be the central motivation for all organic action. All homeos ...
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Frog
A frog is any member of a diverse and largely Carnivore, carnivorous group of short-bodied, tailless amphibians composing the order (biology), order Anura (ανοὐρά, literally ''without tail'' in Ancient Greek). The oldest fossil "proto-frog" ''Triadobatrachus'' is known from the Early Triassic of Madagascar, but molecular clock, molecular clock dating suggests their split from other amphibians may extend further back to the Permian, 265 Myr, million years ago. Frogs are widely distributed, ranging from the tropics to subarctic regions, but the greatest concentration of species diversity is in tropical rainforest. Frogs account for around 88% of extant amphibian species. They are also one of the five most diverse vertebrate orders. Warty frog species tend to be called toads, but the distinction between frogs and toads is informal, not from Taxonomy (biology), taxonomy or evolutionary history. An adult frog has a stout body, protruding eyes, anteriorly-attached tongue, limb ...
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Comparative Physiology
Comparative physiology is a subdiscipline of physiology that studies and exploits the diversity of functional characteristics of various kinds of organisms. It is closely related to evolutionary physiology and environmental physiology. Many universities offer undergraduate courses that cover comparative aspects of animal physiology. According to Clifford Ladd Prosser, "Comparative Physiology is not so much a defined discipline as a viewpoint, a philosophy." History Originally, as narrated in a recent history of the field, physiology focused primarily on human beings, in large part from a desire to improve medical practices. When physiologists first began comparing different species it was sometimes out of simple curiosity to understand how organisms work but also stemmed from a desire to discover basic physiological principles. This use of specific organisms convenient to study specific questions is known as the Krogh Principle. Methodology C. Ladd Prosser, a founder of mo ...
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Aarhus
Aarhus (, , ; officially spelled Århus from 1948 until 1 January 2011) is the second-largest city in Denmark and the seat of Aarhus Municipality. It is located on the eastern shore of Jutland in the Kattegat sea and approximately northwest of Copenhagen. The largest city in Jutland, Aarhus anchors the Central Denmark Region and the statistical region ' (''LØ'') (lit.: Province East Jutland). The LØ is the second most populous statistical region in Denmark with an estimated population of 903,974 (). Aarhus Municipality defines the greater Aarhus area as itself and eight adjacent municipalities totalling 952,824 inhabitants () which is roughly analogous to the municipal and commercial collaboration Business Region Aarhus. The city proper, with an estimated population of 285,273 inhabitants (), ranks as the 2nd-largest city in Denmark. Aarhus dates back to at least the late 8th century and is among the oldest cities in Denmark. It was founded as a harbour settlement at t ...
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Aarhus Katedralskole
Aarhus Katedralskole is a cathedral school, an institution of secondary education, a Danish Gymnasium and a listed building in Aarhus, Denmark. The school is situated in the neighborhood Midtbyen, in the Latin Quarter, bounded by the streets Mejlgade, ''Kystvejen'' and ''Skolegyde''. Aarhus Katedralskole offers the 3 year Matriculation examination (STX) programme with elective subjects in the natural sciences, social sciences and arts. The school is an independent self-owning institution financed by the Danish state with about 800 students divided across 30 classes. History Aarhus Katedralskole was founded in at least 1195 and has continuously worked as a school until present. The exact date of foundation is not known but on 9 February 1195, the bishop of Aarhus, Peder Vognsen, donated his books to the Aarhus Cathedral. The cathedral itself was first completed in 1300, but construction of it began around the same time. During the reformation the school was confiscated by the Cro ...
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Romani People
The Romani (also spelled Romany or Rromani , ), colloquially known as the Roma, are an Indo-Aryan peoples, Indo-Aryan ethnic group, traditionally nomadic Itinerant groups in Europe, itinerants. They live in Europe and Anatolia, and have Romani diaspora, diaspora populations located worldwide, with significant concentrations in the Americas. In the English language, the Romani people are widely known by the Exonym and endonym, exonym Gypsies (or Gipsies), which is considered pejorative by many Romani people due to its connotations of illegality and irregularity as well as its historical use as a list of ethnic slurs, racial slur. For versions (some of which are cognates) of the word in many other languages (e.g., , , it, zingaro, , and ) this perception is either very small or non-existent. At the first World Romani Congress in 1971, its attendees unanimously voted to reject the use of all exonyms for the Romani people, including ''Gypsy'', due to their aforementioned nega ...
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