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(von Zumbusch) Acute Generalized Pustular Psoriasis
VON ZUMBUSCH (ACUTE) GENERALIZED PUSTULAR PSORIASIS, (ACUTE GPP) is the most severe form of generalized pustular psoriasis , and can be associated with life-threatening complications. CONTENTS * 1 Characteristics * 2 Diagnosis * 3 Treatment * 4 History * 5 References CHARACTERISTICSPatients with acute GPP experience the eruption of multiple isolated sterile pustules generalized over the body, recurrent fevers, fatigue, and laboratory abnormalities (elevated ESR , elevated CRP , combined with leukocytosis). DIAGNOSISKogoj's spongiform pustules can be observed via histopathology to confirm acute GPP. TREATMENTAcute GPP typically requires inpatient management including both topical and systemic therapy, and supportive measures. Systemic glucocorticoid withdrawal is a common causative agent. Withdrawal or administration of certain drugs in the patient's previous medication regimen may be required
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International Standard Book Number
The INTERNATIONAL STANDARD BOOK NUMBER (ISBN) is a unique numeric commercial book identifier. An ISBN is assigned to each edition and variation (except reprintings) of a book. For example, an e-book , a paperback and a hardcover edition of the same book would each have a different ISBN. The ISBN is 13 digits long if assigned on or after 1 January 2007, and 10 digits long if assigned before 2007. The method of assigning an ISBN is nation-based and varies from country to country, often depending on how large the publishing industry is within a country. The initial ISBN configuration of recognition was generated in 1967 based upon the 9-digit STANDARD BOOK NUMBERING (SBN) created in 1966. The 10-digit ISBN format was developed by the International Organization for Standardization (ISO) and was published in 1970 as international standard ISO 2108 (the SBN code can be converted to a ten digit ISBN by prefixing it with a zero)
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Special
SPECIAL or SPECIALS may refer to: CONTENTS * 1 Music * 2 Film and television * 3 Other uses * 4 See also MUSIC * _Special_ (album) , a 1992 album by Vesta Williams * "Special" (Garbage song) , 1998 * "Special" (Mew song) , 2005 * "Special" (Stephen Lynch song) , 2000 * The Specials , a British band * "Special", a song by Violent Femmes on _The Blind Leading the Naked _ * "Special", a song on _ The Documentary _ album by GameFILM AND TELEVISION * Special (lighting) , a stage light that is used for a single, s
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Oclc
OCLC, currently incorporated as OCLC
OCLC
ONLINE COMPUTER LIBRARY CENTER, INCORPORATED, is an American nonprofit cooperative organization "dedicated to the public purposes of furthering access to the world's information and reducing information costs". It was founded in 1967 as the OHIO COLLEGE LIBRARY CENTER. OCLC
OCLC
and its member libraries cooperatively produce and maintain WorldCat , the largest online public access catalog (OPAC) in the world. OCLC
OCLC
is funded mainly by the fees that libraries have to pay for its services (around $200 million annually as of 2016 )
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Pubmed Identifier
PUBMED is a free search engine accessing primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institutes of Health maintains the database as part of the Entrez system of information retrieval . From 1971 to 1997, MEDLINE online access to the MEDLARS Online computerized database primarily had been through institutional facilities, such as university libraries . PubMed, first released in January 1996, ushered in the era of private, free, home- and office-based MEDLINE searching. The PubMed system was offered free to the public in June 1997, when MEDLINE searches via the Web were demonstrated, in a ceremony, by Vice President Al Gore
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Digital Object Identifier
In computing, a DIGITAL OBJECT IDENTIFIER or DOI is a persistent identifier or handle used to uniquely identify objects, standardized by the ISO . An implementation of the Handle System , DOIs are in wide use mainly to identify academic, professional, and government information, such as journal articles, research reports and data sets, and official publications though they also have been used to identify other types of information resources, such as commercial videos. A DOI aims to be "resolvable", usually to some form of access to the information object to which the DOI refers. This is achieved by binding the DOI to metadata about the object, such as a URL , indicating where the object can be found. Thus, by being actionable and interoperable, a DOI differs from identifiers such as ISBNs and ISRCs which aim only to uniquely identify their referents. The DOI system uses the indecs Content Model for representing metadata
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International Standard Serial Number
An INTERNATIONAL STANDARD SERIAL NUMBER (ISSN) is an eight-digit serial number used to uniquely identify a serial publication . The ISSN is especially helpful in distinguishing between serials with the same title. ISSN are used in ordering, cataloging, interlibrary loans, and other practices in connection with serial literature. The ISSN system was first drafted as an International Organization for Standardization (ISO) international standard in 1971 and published as ISO 3297 in 1975. ISO subcommittee TC 46/SC 9 is responsible for maintaining the standard. When a serial with the same content is published in more than one media type , a different ISSN is assigned to each media type. For example, many serials are published both in print and electronic media . The ISSN system refers to these types as PRINT ISSN (P-ISSN) and ELECTRONIC ISSN (E-ISSN), respectively
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ICD-10
ICD-10 is the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. The code set allows more than 14,400 different codes and permits the tracking of many new diagnoses . The codes can be expanded to over 16,000 codes by using optional sub-classifications. The WHO provides detailed information about ICD online, and makes available a set of materials online, such as an ICD-10 online browser, ICD-10 Training, ICD-10 online training, ICD-10 online training support, and study guide materials for download
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International Statistical Classification Of Diseases And Related Health Problems
CLASSIFICATION is a general process related to categorization , the process in which ideas and objects are recognized, differentiated, and understood. A CLASSIFICATION SYSTEM is an approach to accomplishing classification
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Erythrocyte Sedimentation Rate
The ERYTHROCYTE SEDIMENTATION RATE (ESR) is the rate at which red blood cells sediment in a period of one hour. It is a common hematology test, and is a non-specific measure of inflammation . To perform the test, anticoagulated blood was traditionally placed in an upright tube, known as a Westergren tube, and the rate at which the red blood cells fall was measured and reported in mm/h. Since the introduction of automated analyzers into the clinical laboratory, the ESR test has been automatically performed. The ESR is governed by the balance between pro-sedimentation factors, mainly fibrinogen , and those factors resisting sedimentation, namely the negative charge of the erythrocytes (zeta potential ). When an inflammatory process is present, the high proportion of fibrinogen in the blood causes red blood cells to stick to each other. The red cells form stacks called 'rouleaux ,' which settle faster, due to their increased density
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C-reactive Protein
1B09, 1GNH, 1LJ7, 3L2Y, 3PVN, 3PVO IDENTIFIERS ALIASES CRP, PTX1, C-reactive protein, pentraxin-related, C-Reactive Protein EXTERNAL IDS OMIM: 123260 MGI: 88512 HomoloGene: 128039 GeneCards: CRP GENE LOCATION (HUMAN) CHR. Chromosome 1 (human) BAND n/a START 159,712,289 bp END 159,714,589 bp GENE LOCATION (MOUSE) CHR
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Generalized Pustular Psoriasis
GENERALIZED PUSTULAR PSORIASIS (GPP) is an extremely rare type of psoriasis that can present in a variety of forms. Unlike the most general and common forms of psoriasis, GPP usually covers the entire body and with pus-filled blisters rather than plaques. GPP can present at any age, but is rarer in young children. It can appear with or without previous psoriasis conditions or history, and can reoccur in periodic episodes. CONTENTS * 1 Signs and Symptoms * 2 Severity * 3 Classification * 3.1 von Zumbusch acute generalized pustular psoriasis * 3.2 Generalized pustular psoriasis of pregnancy (Impetigo herpetiformis) * 3.3 Infantile and juvenile * 3.4 Circinate and annular * 4 Causes * 5 Treatments * 6 Case Reports * 6.1 Case Report 1 * 6.2 Case Report 2 * 6.3 Case Report 3 * 6.4 Case Report 4 * 6.5 Case Report 5 * 7 See also * 8 References SIGNS AND SYMPTOMSGPP presents as pustules and plaques over a wide area of the body
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(von Zumbusch) Acute Generalized Pustular Psoriasis
VON ZUMBUSCH (ACUTE) GENERALIZED PUSTULAR PSORIASIS, (ACUTE GPP) is the most severe form of generalized pustular psoriasis , and can be associated with life-threatening complications. CONTENTS * 1 Characteristics * 2 Diagnosis * 3 Treatment * 4 History * 5 References CHARACTERISTICSPatients with acute GPP experience the eruption of multiple isolated sterile pustules generalized over the body, recurrent fevers, fatigue, and laboratory abnormalities (elevated ESR , elevated CRP , combined with leukocytosis). DIAGNOSISKogoj's spongiform pustules can be observed via histopathology to confirm acute GPP. TREATMENTAcute GPP typically requires inpatient management including both topical and systemic therapy, and supportive measures. Systemic glucocorticoid withdrawal is a common causative agent. Withdrawal or administration of certain drugs in the patient's previous medication regimen may be required
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